2022
Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials
Caruana DL, Gouzoulis MJ, McLaughlin WM, Grauer JN. Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials. Journal Of Shoulder And Elbow Surgery 2022, 31: 1922-1928. PMID: 35398166, DOI: 10.1016/j.jse.2022.02.030.Peer-Reviewed Original ResearchConceptsIndependent predictorsTrial characteristicsClinical trialsTrial terminationOdds of terminationClinical trial completionRetention of participantsResults databaseInterventional studyTrial completionMultivariate analysisAssess reasonsLogistic regressionRecruitment statusTrialsSearch termsParticipant recruitmentPredictorsShoulderIndustry sponsorshipOddsTotalCurrent studyRegistryBlinding
2017
Treatments of Missing Values in Large National Data Affect Conclusions: The Impact of Multiple Imputation on Arthroplasty Research
Ondeck NT, Fu MC, Skrip LA, McLynn RP, Su EP, Grauer JN. Treatments of Missing Values in Large National Data Affect Conclusions: The Impact of Multiple Imputation on Arthroplasty Research. The Journal Of Arthroplasty 2017, 33: 661-667. PMID: 29153865, DOI: 10.1016/j.arth.2017.10.034.Peer-Reviewed Original ResearchConceptsUnicompartmental knee arthroplastyPreoperative albuminAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement ProgramComplete case analysisHematocrit valuesSurgical Quality Improvement ProgramDemographics of patientsPreoperative laboratory valuesMultiple imputationQuality Improvement ProgramArthroplasty researchSelection biasHealthy patientsLaboratory valuesPotential selection biasPatientsJoint surgeonsComplete dataArthroplastyOnly caseNational datasetOutcomesConclusion