Effect of daily parathyroid hormone (1–34) on lumbar fusion in a rat model
Lawrence JP, Ennis F, White AP, Magit D, Polzhofer G, Drespe I, Troiano NW, Grauer JN. Effect of daily parathyroid hormone (1–34) on lumbar fusion in a rat model. The Spine Journal 2006, 6: 385-390. PMID: 16825043, DOI: 10.1016/j.spinee.2005.10.010.Peer-Reviewed Original ResearchConceptsSerum osteocalcin levelsParathyroid hormoneOsteocalcin levelsFusion rateDaily injectionsManual palpationLumbar fusionRat modelIntertransverse process spinal fusionDaily parathyroid hormoneSpinal fusion outcomesPosterolateral lumbar fusionIliac crest autograftSprague-Dawley ratsPreclinical animal studiesGreater fusion rateGreat clinical valuePlacebo groupIntermittent administrationSerum osteocalcinCrest autograftAnabolic effectsSpinal fusionInjectable agentsClinical value