2009
Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model.
Miller CP, Simpson AK, Whang PG, Erickson BP, Waked WR, Lawrence JP, Grauer JN. Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model. The American Journal Of Orthopedics 2009, 38: 578-84. PMID: 20049353.Peer-Reviewed Original ResearchConceptsLocal infectionRecombinant human bone morphogenetic proteinEarly deathRabbit posterolateral lumbar fusion modelPosterolateral lumbar fusion modelRhBMP-2Postoperative infectionSurgical infectionsSpine surgeryAutograft groupSpinal arthrodesisSterile salineFusion rateAutograftRecombinant human bone morphogenetic protein-2InfectionHuman bone morphogenetic proteinHuman bone morphogenetic protein-2Bone formationProtein 2Staphylococcus aureusRabbitsBone morphogenetic protein-2Bone morphogenetic proteinMorphogenetic protein-2
2007
The safety and utility of bone morphogenetic protein in anterior and posterior cervical-spine fusions
Lee R, White A, Grauer J. The safety and utility of bone morphogenetic protein in anterior and posterior cervical-spine fusions. Current Orthopaedic Practice 2007, 18: 270-275. DOI: 10.1097/bco.0b013e32810c00f6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCervical spine surgeryRecombinant human bone morphogenetic proteinHuman bone morphogenetic proteinAnterior cervical spine surgeryAutologous bone graft harvestPosterior cervical spine fusionBone morphogenetic proteinSoft tissue edemaProspective clinical studyCervical spine fusionHigh fusion rateBone graft harvestMorphogenetic proteinsLocal complicationsBone graft alternativesCervical fusionCohort studyBony unionCervical spineClinical studiesSurgical techniqueLumbar spineAppropriate dosePurpose of ReviewInterestLocal swelling
2006
Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery
White A, Lee R, Grauer J. Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery. Seminars In Spine Surgery 2006, 18: 207-210. DOI: 10.1053/j.semss.2006.09.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCervical spine surgeryRevision cervical spine surgeryAnterior cervical spine surgeryRecombinant human bone morphogenetic proteinSpine surgeryProspective clinical studyOff-label useBone morphogenetic proteinCervical surgeryBone graft alternativesPseudarthrosis repairClinical studiesSurgical techniqueAppropriate doseAnimal modelsSurgeryGraft alternativesHuman bone morphogenetic proteinMorphogenetic proteinsPotent osteoinductive factorsRecent reportsOsteoinductive factorsComplicationsPseudarthrosesDose