2006
Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery
White A, Lee R, Grauer J. Bone Morphogenetic Protein for Pseudarthrosis Repair in Revision Cervical Spine Surgery. Seminars In Spine Surgery 2006, 18: 207-210. DOI: 10.1053/j.semss.2006.09.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCervical spine surgeryRevision cervical spine surgeryAnterior cervical spine surgeryRecombinant human bone morphogenetic proteinSpine surgeryProspective clinical studyOff-label useBone morphogenetic proteinCervical surgeryBone graft alternativesPseudarthrosis repairClinical studiesSurgical techniqueAppropriate doseAnimal modelsSurgeryGraft alternativesHuman bone morphogenetic proteinMorphogenetic proteinsPotent osteoinductive factorsRecent reportsOsteoinductive factorsComplicationsPseudarthrosesDose
2004
Development of a New Zealand White Rabbit Model of Spinal Pseudarthrosis Repair and Evaluation of the Potential Role of OP-1 to Overcome Pseudarthrosis
Grauer JN, Vaccaro AR, Kato M, Kwon BK, Beiner JM, Patel TC, Hilibrand AS, Chiba K, Albert TJ. Development of a New Zealand White Rabbit Model of Spinal Pseudarthrosis Repair and Evaluation of the Potential Role of OP-1 to Overcome Pseudarthrosis. Spine 2004, 29: 1405-1412. PMID: 15223930, DOI: 10.1097/01.brs.0000129028.25671.96.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone Morphogenetic Protein 7Bone Morphogenetic ProteinsCotinineDrug Evaluation, PreclinicalFemaleHumansIliumInfusion Pumps, ImplantableLumbar VertebraeNicotinePostoperative ComplicationsPseudarthrosisRabbitsRadiographyRecombinant ProteinsSingle-Blind MethodSpinal DiseasesSpinal FusionTransforming Growth Factor betaTransplantation, AutologousWound HealingConceptsNew Zealand white rabbitsPosterolateral lumbar fusionOsteogenic protein-1Zealand white rabbitsLumbar fusionPseudarthrosis repairFusion massFusion rateWhite rabbitsManual palpationIliac crest autograftNew Zealand white rabbit modelTreatment of pseudarthrosesRabbit fusion modelWhite rabbit modelPresence of nicotineCrest autograftBACKGROUND DATAPseudarthrosesComputed tomographyAnimal modelsRabbit modelAutograftGraftWeeks