2006
Osteogenic Protein-1 Induced Gene Expression: Evaluation in a Posterolateral Spinal Pseudarthrosis Model
White AP, Maak TG, Prince D, Vaccaro AR, Albert TJ, Hilibrand AS, Grauer JN. Osteogenic Protein-1 Induced Gene Expression: Evaluation in a Posterolateral Spinal Pseudarthrosis Model. Spine 2006, 31: 2550-2555. PMID: 17047543, DOI: 10.1097/01.brs.0000240713.24367.42.Peer-Reviewed Original ResearchConceptsGene expressionOsteogenic protein-1Protein 1Differential gene expressionGlyceraldehyde-3-phosphate dehydrogenaseGene expression dataBone morphogenetic protein-2Morphogenetic protein-2Platelet-derived growthExpression dataTranscriptase-polymerase chain reactionPolymerase chain reactionMolecular studiesProtein 2Messenger ribonucleic acidRibonucleic acidChain reactionAdhesion moleculesCytokine gene expressionExpressionGrowth factorVascular endothelial growth factorEnhanced levelsEndothelial growth factorReverse transcriptase-polymerase chain reaction
2001
Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion
Patel T, Erulkar J, Grauer J, Troiano N, Panjabi M, Friedlaender G. Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion. Spine 2001, 26: 1656-1661. PMID: 11474350, DOI: 10.1097/00007632-200108010-00004.Peer-Reviewed Original ResearchConceptsPosterolateral lumbar fusionOsteogenic protein-1Inhibitory effectProtein 1Lumbar fusionRabbit posterolateral lumbar fusion modelRabbit posterolateral spine fusion modelFusion massRabbit modelSubcutaneous mini-osmotic pumpsPosterolateral lumbar fusion modelMini-osmotic pumpsNew Zealand white rabbitsNew Zealand white rabbit modelZealand white rabbitsPosterolateral spine fusionSpine fusion modelPosterolateral intertransverse process fusionWhite rabbit modelPresence of nicotineIntertransverse process fusionBone graft alternativesBony fusionBACKGROUND DATASpine fusion