2022
Chondrosarcoma patient characteristics, management, and outcomes based on over 5,000 cases from the National Cancer Database (NCDB)
Ottesen TD, Shultz BN, Munger AM, Amick M, Toombs CS, Friedaender GE, Grauer JN. Chondrosarcoma patient characteristics, management, and outcomes based on over 5,000 cases from the National Cancer Database (NCDB). PLOS ONE 2022, 17: e0268215. PMID: 35901087, PMCID: PMC9333210, DOI: 10.1371/journal.pone.0268215.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseLong-term survivalMultivariate Cox analysisDistant metastasisSurgical treatmentChondrosarcoma patientsCox analysisCancer DatabaseLong-term survival dataKaplan-Meier survival curvesKaplan-Meier survival analysisPrimary osseous tumorsMainstay of treatmentExtent of diseasePoor prognostic factorPrimary tumor siteAge categoriesLikelihood of deathAxial involvementPatient characteristicsWorse survivalPrognostic factorsSurgical excisionMale sexOsseous tumors
2016
A Genetic Test Predicts Providence Brace Success for Adolescent Idiopathic Scoliosis When Failure Is Defined as Progression to >45 Degrees
Bohl DD, Telles CJ, Ruiz FK, Badrinath R, DeLuca PA, Grauer JN. A Genetic Test Predicts Providence Brace Success for Adolescent Idiopathic Scoliosis When Failure Is Defined as Progression to >45 Degrees. Clinical Spine Surgery A Spine Publication 2016, 29: e146-e150. PMID: 27007790, DOI: 10.1097/bsd.0b013e3182aa4ce1.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisPotential confoundingIdiopathic scoliosisGenetic testsRetrospective cohort studyMainstay of treatmentRisk of progressionCohort studyEligible subjectsRetrospective cohortAIS patientsPotential confoundersClinical managementAvailable genetic testsBACKGROUND DATAGenetic predispositionPatientsClinical practiceSaliva samplesScoliScoreProvidence braceGenetic factorsPolygenic fashionScoliosisProgression
2010
Contemporary Management of Symptomatic Lumbar Disc Herniations
Jegede KA, Ndu A, Grauer JN. Contemporary Management of Symptomatic Lumbar Disc Herniations. Orthopedic Clinics Of North America 2010, 41: 217-224. PMID: 20399360, DOI: 10.1016/j.ocl.2010.01.003.Peer-Reviewed Original ResearchConceptsLumbar disc herniationSymptomatic disc herniationDisc herniationClinical presentationSurgical interventionSymptomatic lumbar disc herniationMainstay of treatmentCommon clinical entityPatient's clinical presentationMagnetic resonance imagingClinical entityAsymptomatic individualsLumbar discectomyTreatment optionsConservative measuresSignificant symptomsPhysical therapyHerniationMajor abnormalitiesResonance imagingContemporary managementSymptomsPatientsInterventionDiscectomy