2022
General Versus Neuraxial Anesthesia in Revision Surgery for Periprosthetic Joint Infection
Serino J, Galivanche AR, Grauer JN, Haynes M, Karas V, Della Valle CJ. General Versus Neuraxial Anesthesia in Revision Surgery for Periprosthetic Joint Infection. The Journal Of Arthroplasty 2022, 37: s971-s976. PMID: 35017049, DOI: 10.1016/j.arth.2022.01.002.Peer-Reviewed Original ResearchConceptsPeriprosthetic joint infectionNeuraxial anesthesiaAdverse eventsGeneral anesthesiaRevision surgeryJoint infectionLower riskNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsSerious adverse eventsThirty-day outcomesImprovement Program databasePropensity-score matchingIntraspinal abscessProgram databaseRevision arthroplastyAmerican CollegeAnesthesiaMultivariate analysisProcedural variablesSurgeryPatientsInfection
2014
CORR Insights®: Incidence of Surgical Site Infection After Spine Surgery: What Is the Impact of the Definition of Infection?
Grauer JN, Samuel AM. CORR Insights®: Incidence of Surgical Site Infection After Spine Surgery: What Is the Impact of the Definition of Infection? Clinical Orthopaedics And Related Research® 2014, 473: 1620-1621. PMID: 25315280, PMCID: PMC4385354, DOI: 10.1007/s11999-014-4002-2.Peer-Reviewed Original Research
2009
Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model.
Miller CP, Simpson AK, Whang PG, Erickson BP, Waked WR, Lawrence JP, Grauer JN. Effects of recombinant human bone morphogenetic protein 2 on surgical infections in a rabbit posterolateral lumbar fusion model. The American Journal Of Orthopedics 2009, 38: 578-84. PMID: 20049353.Peer-Reviewed Original ResearchConceptsLocal infectionRecombinant human bone morphogenetic proteinEarly deathRabbit posterolateral lumbar fusion modelPosterolateral lumbar fusion modelRhBMP-2Postoperative infectionSurgical infectionsSpine surgeryAutograft groupSpinal arthrodesisSterile salineFusion rateAutograftRecombinant human bone morphogenetic protein-2InfectionHuman bone morphogenetic proteinHuman bone morphogenetic protein-2Bone formationProtein 2Staphylococcus aureusRabbitsBone morphogenetic protein-2Bone morphogenetic proteinMorphogenetic protein-2
2006
Necrotizing Infection of the Spine
Spock CR, Miki RA, Shah RV, Grauer JN. Necrotizing Infection of the Spine. Spine 2006, 31: e342-e344. PMID: 16688026, DOI: 10.1097/01.brs.0000217631.73632.37.Peer-Reviewed Original ResearchConceptsNecrotizing infectionAggressive surgical debridementMultifocal necrotizing fasciitisMultisystem organ failureSite of involvementDiabetic foot ulcersLumbar involvementSurgical debridementDiabetic patientsNecrotizing fasciitisOrgan failureFoot ulcersFatal conditionCase reportSuch infectionsBACKGROUND DATALumbar spineInfectionPatientsSpinal componentsSoft tissueSpineFasciitisPotential focusGrave consequences
2004
The use of wound vacuums in the management of postoperative wound infections
Husted D, Grauer J, Hilibrand A. The use of wound vacuums in the management of postoperative wound infections. Seminars In Spine Surgery 2004, 16: 182-187. DOI: 10.1053/j.semss.2004.09.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsWound infectionPostoperative wound infectionAppropriate antibiotic coverageWound vacuumAntibiotic coverageDevastating complicationWound checkSpine woundsSecondary intentionPrimary closurePrimary treatmentSpinal surgeryFluid collectionComplex woundsNeural elementsSurgical fieldSoft tissueInfectionWoundsHealingComplicationsDebridementSurgery
2003
Postoperative wound infections of the spine.
Beiner JM, Grauer J, Kwon BK, Vaccaro AR. Postoperative wound infections of the spine. Neurosurgical FOCUS 2003, 15: e14. PMID: 15347232, DOI: 10.3171/foc.2003.15.3.14.BooksMeSH KeywordsAnti-Bacterial AgentsAntibiotic ProphylaxisBlood SedimentationBone TransplantationCombined Modality TherapyComorbidityC-Reactive ProteinDebridementDiagnostic ImagingDisease SusceptibilityDiskectomyDrug Therapy, CombinationEquipment ContaminationHumansInternal FixatorsMalnutritionNutritional SupportReoperationRisk FactorsSpineSurgical Wound InfectionTherapeutic IrrigationConceptsRate of infectionLumbar surgeryWound infectionNutritional statusPostoperative spinal wound infectionsAntibiotic prophylactic therapySpinal wound infectionsPostoperative wound infectionUncomplicated postoperative courseErythrocyte sedimentation rateC-reactive proteinPossibility of infectionMajority of casesSubfascial layerProphylactic therapyAggressive treatmentPostoperative coursePatient factorsWound swellingClinical symptomsSuperficial infectionRisk factorsBone graftInfectionComplete eradication