2024
Sponsorship of Clinical Trials Related to the Shoulder and Elbow: Trends Over Time and Comparative Analysis of Trial Characteristics by Sponsorship Type
Caruana D, Grauer J. Sponsorship of Clinical Trials Related to the Shoulder and Elbow: Trends Over Time and Comparative Analysis of Trial Characteristics by Sponsorship Type. JAAOS Global Research And Reviews 2024, 8: e23.00257. PMID: 38175673, PMCID: PMC10758529, DOI: 10.5435/jaaosglobal-d-23-00257.Peer-Reviewed Original Research
2023
Sponsorship of clinical trials related to the spine: Trends over time and comparative analysis of trial characteristics by sponsorship type
Caruana D, Jiang W, Elaydi A, Grauer J. Sponsorship of clinical trials related to the spine: Trends over time and comparative analysis of trial characteristics by sponsorship type. North American Spine Society Journal (NASSJ) 2023, 17: 100296. PMID: 38130466, PMCID: PMC10733670, DOI: 10.1016/j.xnsj.2023.100296.Peer-Reviewed Original ResearchTrial characteristicsClinical trialsIntervention typePhases of studyTrial registration dataInternet-based registryLack of randomizationCross-sectional analysisResults databaseDifferent intervention typesMultivariate analysisIncomplete reportingTrialsSponsorship typesSpineRandomizationRegistration dataIndustry sponsorshipStart yearRegistry
2022
Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials
Caruana DL, Gouzoulis MJ, McLaughlin WM, Grauer JN. Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials. Journal Of Shoulder And Elbow Surgery 2022, 31: 1922-1928. PMID: 35398166, DOI: 10.1016/j.jse.2022.02.030.Peer-Reviewed Original ResearchConceptsIndependent predictorsTrial characteristicsClinical trialsTrial terminationOdds of terminationClinical trial completionRetention of participantsResults databaseInterventional studyTrial completionMultivariate analysisAssess reasonsLogistic regressionRecruitment statusTrialsSearch termsParticipant recruitmentPredictorsShoulderIndustry sponsorshipOddsTotalCurrent studyRegistryBlindingAnalysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials
Caruana DL, Kim D, Galivanche AR, David WB, Justen MA, Moushey AM, Sheth AH, Paranjpe MD, Grauer JN. Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials. Clinical Spine Surgery A Spine Publication 2022, 35: e596-e600. PMID: 35351841, DOI: 10.1097/bsd.0000000000001323.Peer-Reviewed Original ResearchConceptsClinical trialsTrial terminationTrial characteristicsMultivariate analysisCross-sectional analysisInvestigation of drugsInsufficient accrualResults databaseInterventional studyDetermine predictorsClinical studiesBACKGROUND DATACommon reasonAssess reasonsRecruitment statusTrialsPredictors of terminationSearch termsSpineCompletion ratesRegistryPredictorsStudyTermination
2014
Comparison of the lumbar disc herniation patients randomized in SPORT to 6,846 discectomy patients from NSQIP: demographics, perioperative variables, and complications correlate well
Golinvaux NS, Bohl DD, Basques BA, Yacob A, Grauer JN. Comparison of the lumbar disc herniation patients randomized in SPORT to 6,846 discectomy patients from NSQIP: demographics, perioperative variables, and complications correlate well. The Spine Journal 2014, 15: 685-691. PMID: 25499208, DOI: 10.1016/j.spinee.2014.12.008.Peer-Reviewed Original ResearchConceptsSpine Patient Outcomes Research TrialElective lumbar discectomyDiscectomy patientsPerioperative factorsLumbar discectomyClinical trialsNational Surgical Quality Improvement Program databaseSuperficial wound infection rateQuality Improvement Program databaseLumbar disc herniation patientsHigher body mass indexTotal wound complicationsRetrospective cohort studyDeep wound infectionImprovement Program databaseStatistical differenceWound infection rateAverage operative timeDisc herniation patientsBody mass indexNational patient sampleNinth Revision codesRandomized clinical trialsLength of stayResearch trials