2000
A Primitive ATP Receptor from the Little Skate Raja erinacea *
Dranoff J, O'Neill A, Franco A, Cai S, Connolly G, Ballatori N, Boyer J, Nathanson M. A Primitive ATP Receptor from the Little Skate Raja erinacea *. Journal Of Biological Chemistry 2000, 275: 30701-30706. PMID: 10900200, DOI: 10.1074/jbc.m003366200.Peer-Reviewed Original ResearchConceptsLittle skate Raja erinaceaSkate Raja erinaceaDegenerate oligonucleotide probeRaja erinaceaP2Y receptor pharmacologySingle polymerase chain reaction productXenopus oocyte expression systemLiver cDNA libraryATP receptorsHigher organismsEvolutionary forerunnerCommon ancestorOocyte expression systemPhylogenetic analysisP2Y receptorsCDNA clonesPrimitive organismsCDNA libraryGene productsSubstrate preferenceMolecular basisExpression systemNucleotide specificityMammalian tissuesRange of nucleotides
1999
Expression and subcellular localization of the ryanodine receptor in rat pancreatic acinar cells.
Leite MF, Dranoff JA, Gao L, Nathanson MH. Expression and subcellular localization of the ryanodine receptor in rat pancreatic acinar cells. Biochemical Journal 1999, 337 ( Pt 2): 305-9. PMID: 9882629, PMCID: PMC1219966, DOI: 10.1042/0264-6021:3370305.Peer-Reviewed Original ResearchConceptsPancreatic acinar cellsNon-excitable cell typesCell typesCell types resultsAcinar cellsNon-excitable cellsRyanodine receptorSubcellular localizationPolarized epitheliumReverse transcription-PCRRat pancreatic acinar cellsTrisphosphate receptorCo-ordinated releaseType 2 RyRExcitable cellsRelease pathwayTranscription-PCRPrincipal Ca2Release channelApical regionCytosolic Ca2CellsFundamental roleRyRsPropagation of Ca2