2014
Expression of mediators of purinergic signaling in human liver cell lines
Goree JR, Lavoie EG, Fausther M, Dranoff JA. Expression of mediators of purinergic signaling in human liver cell lines. Purinergic Signalling 2014, 10: 631-638. PMID: 25194703, PMCID: PMC4272373, DOI: 10.1007/s11302-014-9425-4.Peer-Reviewed Original ResearchConceptsLiver cell subpopulationsPurinergic signalingPurinergic signalsCell subpopulationsCell linesExpression of mediatorsLiver disease pathogenesisHuman liver cell lineHuman cell line modelsCell line modelsLiver cell lineHepatic functionP2Y receptorsP2X receptorsLX-2Disease pathogenesisAdenosine receptorsLiver physiologyRT-PCRReceptorsHuman cell linesPurinergicLiverSubpopulationsSignaling
2012
Role of purinergic P2X receptors in the control of liver homeostasis
Fausther M, Gonzales E, Dranoff JA. Role of purinergic P2X receptors in the control of liver homeostasis. Wiley Interdisciplinary Reviews Membrane Transport And Signalling 2012, 1: 341-348. PMID: 22662313, PMCID: PMC3364537, DOI: 10.1002/wmts.32.Peer-Reviewed Original ResearchBasic cellular functionsIntracellular signal transduction pathwaysNumerous membrane transportersSignal transduction pathwaysLiver homeostasisPurinergic signalingCellular functionsP2Y receptorsTissue homeostasisTransduction pathwaysP2X receptorsHepatic cellsMembrane transportersMammalian speciesCell cycleSignaling pathwaysSalvage pathwayProtein synthesisCell typesATP moleculesFunctional relevanceExtracellular mediumMembrane levelGlucose/lipid metabolismDifferent liver cell types