2020
Purinergic Regulation of Bile Ductular Secretion
Dranoff J. Purinergic Regulation of Bile Ductular Secretion. 2020, 96-104. DOI: 10.1201/9780367813888-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsP2Y receptorsPurinergic receptorsIntestinal epitheliumExtracellular nucleotidesP2Y receptor subtypesP2 receptorsReceptor subtypesRespiratory epitheliumP1 receptorsMucin secretionNucleotide receptorsPurinergic agonistsPlatelet aggregationPurinergic regulationChloride secretionDistinct receptorsDuctular secretionNucleoside receptorsEpithelial secretionEpitheliumReceptorsSalivary glandsSecretionSecretory epitheliumRenal epithelium
2011
Coexpression of ecto-5′-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver
Fausther M, Lecka J, Soliman E, Kauffenstein G, Pelletier J, Sheung N, Dranoff JA, Sévigny J. Coexpression of ecto-5′-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver. AJP Gastrointestinal And Liver Physiology 2011, 302: g447-g459. PMID: 22135310, PMCID: PMC3287391, DOI: 10.1152/ajpgi.00165.2011.Peer-Reviewed Original ResearchConceptsRat liverRecombinant rat enzymeDistinct fibroblast populationsP2 receptor agonistsSmooth muscle cellsNTPDase2/CD39L1Vascular endothelial cellsFibrotic rat liverCD73 protein expressionSpecific biochemical propertiesPortal fibroblastsReceptor agonistP2 receptorsNormal rat liverFibrotic conditionsPortal spacesInhibitor ADPAdenosine formationMuscle cellsCD73Endothelial cellsTriphosphate diphosphohydrolaseFormation of adenosineProtein expressionEctonucleotidases