Contribution of Myofibroblasts of Different Origins to Liver Fibrosis
Fausther M, Lavoie EG, Dranoff JA. Contribution of Myofibroblasts of Different Origins to Liver Fibrosis. Current Pathobiology Reports 2013, 1: 225-230. PMID: 23997993, PMCID: PMC3755779, DOI: 10.1007/s40139-013-0020-0.Peer-Reviewed Original ResearchHepatic fibrosisLiver fibrosisLiver myofibroblastsContribution of myofibroblastsProgressive liver fibrosisPrimary effector cellsTissue repair responseExtracellular matrix accumulationMajor fibrogenic cellsLiver failureLiver injuryEffector cellsCurrent therapiesAntifibrotic therapyCommon causeScar formationFibrogenic cellsFibrosisMatrix accumulationExtracellular matrix synthesisMyofibroblastsPromising targetWound healingRepair responseTherapy