2022
Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro
Uthaya Kumar DB, Motakis E, Yurieva M, Kohar V, Martinek J, Wu TC, Khoury J, Grassmann J, Lu M, Palucka K, Kaminski N, Koff JL, Williams A. Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2022, 322: l822-l841. PMID: 35438006, PMCID: PMC9142163, DOI: 10.1152/ajplung.00254.2021.Peer-Reviewed Original ResearchMeSH KeywordsEpithelial CellsEpithelial-Mesenchymal TransitionEpitheliumHumansLung DiseasesRespiratory MucosaRNA, Long NoncodingConceptsProtein codingEpithelial-mesenchymal transitionLncRNA genesEMT inductionSingle-cell RNA sequencingSingle-cell RNA-seq dataEpithelial-mesenchymal plasticityRNA-seq dataMechanisms of EMTSingle-cell levelEpithelial cell typesRole of EMTTranscriptional reprogrammingHuman bronchial epithelial cellsRNA genesEMT gene signatureTranscriptional changesTranscriptional differencesRNA sequencingSpecific lncRNAsBronchial epithelial cellsDifferential expressionMyofibroblast conversionCell typesGenes
2006
Case Report: A Case of Wood-Smoke–Related Pulmonary Disease
Diaz J, Koff J, Gotway M, Nishimura S, Balmes J. Case Report: A Case of Wood-Smoke–Related Pulmonary Disease. Environmental Health Perspectives 2006, 114: 759-762. PMID: 16675433, PMCID: PMC1459932, DOI: 10.1289/ehp.8489.Peer-Reviewed Original ResearchConceptsPulmonary diseaseThickened bronchovascular bundlesThoracic computed tomographyChronic productive coughChronic obstructive pulmonary diseaseObstructive pulmonary diseaseHealth care providersBiomass smokeExposure to biomass smokeLung biopsyProductive coughBronchovascular bundlesPulmonary nodulesLung cancerPulmonary clinicClinical progressionCarbon-laden macrophagesRespiratory manifestationsBlack plaqueHistopathological abnormalitiesFibrotic scarLung parenchymaMild symptomsAmount of smokingCare providers