2022
Role of intracortical neuropil growth in the gyrification of the primate cerebral cortex
Rash B, Arellano J, Duque A, Rakic P. Role of intracortical neuropil growth in the gyrification of the primate cerebral cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 120: e2210967120. PMID: 36574666, PMCID: PMC9910595, DOI: 10.1073/pnas.2210967120.Peer-Reviewed Original ResearchConceptsOuter subventricular zoneSubcortical white matterCerebral cortexWhite matterFormation of gyriPrimate cerebral cortexMammalian cerebral cortexMarkers of proliferationCortical malformationsCortical plateGlial cellsGyral developmentSubventricular zoneCortical neurogenesisFetal developmentVentricular zoneCortical foldingNeuronal progenitorsGyrificationNeuronal growthNeuropil growthPrimary gyriCortexNeurodevelopmental disordersGyrus
2002
Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex
DeFelipe J, Arellano J, Merchán-Pérez A, González-Albo M, Walton K, Llinás R. Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex. Cerebral Cortex 2002, 12: 883-891. PMID: 12122037, DOI: 10.1093/cercor/12.8.883.Peer-Reviewed Original ResearchConceptsLayers II/IIISynaptic circuitrySynaptic densityFlight animalsLaminar-specific mannerLower synaptic densityDensity of synapsesDays of spaceflightAsymmetrical synapsesCortical synapsesLayer IVCortical synaptogenesisLong-term spaceflightControl animalsDeveloping NeocortexAdult patternCortical organizationNeocortical circuitrySynapsesGround control animalsMonth periodSignificant differencesFuture long-term spaceflightsAnimalsNeocortical representationsMicrostructure of the neocortex: Comparative aspects
DeFelipe J, Alonso-Nanclares L, Arellano J. Microstructure of the neocortex: Comparative aspects. Brain Cell Biology 2002, 31: 299-316. PMID: 12815249, DOI: 10.1023/a:1024130211265.Peer-Reviewed Original ResearchConceptsDifferent cortical areasCortical areasExtrinsic afferent systemsNeocortex of humansInhibitory GABAergic interneuronsDensity of excitatoryNumber of synapsesSpecific cortical circuitsDistinct cortical areasSpiny cellsInhibitory circuitsGABAergic interneuronsInhibitory synapsesNeocortical neuronsNeuronal elementsPyramidal cellsAfferent systemsCortical circuitsNeocortical circuitsCortical tissueNumber of neuronsNeocortexNeuronsExcitatoryBasic microcircuit