Neuronal loss from the subthalamic nuclei in a patient with progressive chorea
Sinard J, Hedreen J. Neuronal loss from the subthalamic nuclei in a patient with progressive chorea. Movement Disorders 1995, 10: 305-311. PMID: 7651448, DOI: 10.1002/mds.870100313.Peer-Reviewed Original ResearchConceptsSubthalamic nucleusNeuronal lossMultiple neurological deficitsPatterns of injuryPurkinje cell lossBilateral choreaChronic phenytoinNeurological deficitsPeripheral neuropathyProgressive choreaSensory neuropathyPathological findingsProgressive dementiaSeizure disorderBrain syndromePhenytoin toxicityChoreiform movementsAtaxic gaitAutopsy examinationMovement disordersAge 66Pathological basisPatient's brainCognitive declineCell loss