2024
Threats to social safety and neuro-inflammatory mechanisms underlying sexual orientation disparities in depression symptom severity: A prospective cohort study of young adults
Bränström R, Hatzenbuehler M, Lattanner M, Hollinsaid N, McDade T, Pachankis J. Threats to social safety and neuro-inflammatory mechanisms underlying sexual orientation disparities in depression symptom severity: A prospective cohort study of young adults. Brain Behavior And Immunity 2024, 119: 211-219. PMID: 38548185, DOI: 10.1016/j.bbi.2024.03.036.Peer-Reviewed Original ResearchDepressive symptom severitySexual minoritiesChronically elevated inflammationInterpersonal eventsRisk of depressionDepressive symptomsSocial safetySymptom severityElevated inflammationSocial Signal Transduction Theory of DepressionSexual minority individualsElevated risk of depressionSexual orientation disparitiesHeterosexual young adultsChronic inflammationTheory of depressionCohort study of young adultsPopulation-based evidencePre-registered analysesStudy of young adultsSevere depressive symptomsYoung adultsNationally representative sampleProspective cohort studySexual orientation
2021
Early Timing and Determinants of the Sexual Orientation Disparity in Internalizing Psychopathology: A Prospective Cohort Study from Ages 3 to 15
Pachankis JE, Clark KA, Klein DN, Dougherty LR. Early Timing and Determinants of the Sexual Orientation Disparity in Internalizing Psychopathology: A Prospective Cohort Study from Ages 3 to 15. Journal Of Youth And Adolescence 2021, 51: 458-470. PMID: 34731394, PMCID: PMC9307058, DOI: 10.1007/s10964-021-01532-x.Peer-Reviewed Original ResearchConceptsProspective cohort studySexual orientation disparitiesCohort studyAnxiety symptomsDepression symptomsOrientation disparitiesHigher depression symptomsEarly determinantsSymptomsSupportive interventionsAppropriate interventionsOptimal timingAge 15Poor parental relationshipsAge 12Mother-child relationshipAge 3Social stressDepressionInterventionAgeInternalizing psychopathologyDisparitiesPeer victimizationEarly development