IFN-Inducible GTPases in Host Cell Defense
Kim BH, Shenoy AR, Kumar P, Bradfield CJ, MacMicking JD. IFN-Inducible GTPases in Host Cell Defense. Cell Host & Microbe 2012, 12: 432-444. PMID: 23084913, PMCID: PMC3490204, DOI: 10.1016/j.chom.2012.09.007.Peer-Reviewed Original ResearchConceptsGuanylate binding proteinsIFN-inducible GTPasesHuman genome-wide association studiesProtein complex assemblyGenome-wide association studiesPathogen-containing vacuolesHost cell defenseVesicular trafficTranscriptional profilingComplex assemblyCell defenseCell-intrinsic responsesAssociation studiesGTPasesBinding proteinCell interiorIndividual cellsAltered expressionGTPase MDiverse groupCentral roleAutophagicCytosolSpeciesPlants