Neurotransmitter alterations in PTSD: catecholamines and serotonin.
Southwick SM, Paige S, Morgan CA, Bremner JD, Krystal JH, Charney DS. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Seminars In Clinical Neuropsychiatry 1999, 4: 242-8. PMID: 10553029, DOI: 10.153/scnp00400242.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderIntrusive memoriesLevel of alertnessSelective attentionAuditory remindersLife-threatening stimuliStress disorderCatecholamine dysregulationUrine catecholamine excretionExaggerated reactivityDepressed moodExaggerated startlePlatelet paroxetine bindingSerotonergic dysregulationAggressionClinical efficacyImpulsivityMotor outputBlunted prolactin responseMemoryMoodSerotonin reuptake inhibitorsAdrenergic receptor numberCentral catecholamine neuronsCentral nervous system