Associations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults
Jia H, Bao P, Yao S, Zhang X, Mu J, Hu G, Du M, Chu C, Zhang X, Wang L, Liao Y, Wang D, Ma Q, Yan Y, Niu Z, Gao W, Li H, Wu G, Chang J, Wang Y. Associations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults. Hypertension Research 2023, 46: 1795-1803. PMID: 37160967, DOI: 10.1038/s41440-023-01301-2.Peer-Reviewed Original ResearchConceptsLongitudinal BP changesLow-salt dietDevelopment of hypertensionBlood pressureHypertension incidenceBP changesSodium-glucose cotransporter 2 inhibitorsSalt sensitivityCotransporter 2 inhibitorsIncidence of hypertensionHigh-salt dietSystolic blood pressureBlood pressure changesGenetic polymorphismsIncident hypertensionSystolic BPDietary interventionSBP changeUsual dietHypertensionChinese adultsSalutary effectsIncidenceDietSGLT2Reducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow
Holleck M, Tikkanen K, Holleck J, Frank C, Falco N, Cosentino D, Chang J. Reducing Nighttime Interruptions and Improving Sleep for Hospitalized Patients by Restructuring Nighttime Clinical Workflow. Journal Of General Internal Medicine 2023, 38: 2091-2097. PMID: 36697927, PMCID: PMC10361944, DOI: 10.1007/s11606-022-08005-2.Peer-Reviewed Original ResearchConceptsBlood pressure checkPressure checkHospitalized patientsSleep disruptionClinical workflowNighttime sleep disruptionsVenous thromboembolism prophylaxisGeneral medical wardsPercentage of patientsCross-sectional studyVeterans Administration HospitalWorse sleep qualityKey ResultsAfterNocturnal disruptionsTelemetry patientsThromboembolism prophylaxisMedical wardsImproved sleepMedication administrationAdministration HospitalSleep qualityPatientsNighttime disruptionsSleep surveyHospital