Angiopoietin-1, Angiopoietin-2 and Bicarbonate as Diagnostic Biomarkers in Children with Severe Sepsis
Wang K, Bhandari V, Giuliano JS, O′Hern C, Shattuck MD, Kirby M. Angiopoietin-1, Angiopoietin-2 and Bicarbonate as Diagnostic Biomarkers in Children with Severe Sepsis. PLOS ONE 2014, 9: e108461. PMID: 25255212, PMCID: PMC4178003, DOI: 10.1371/journal.pone.0108461.Peer-Reviewed Original ResearchConceptsPediatric intensive care unitSepsis severityAngiopoietin-2Angiopoietin-1Severe pediatric sepsisSeverity of sepsisIntensive care unitTime of admissionHigh mortality rateSevere sepsisPediatric sepsisCare unitAng-2Ill childrenClinical dataAng-1Mortality rateSepsisSingle biomarkerDiagnostic biomarkersBiomarkersSeverityPlasma samplesMultiple biomarkersChildren