Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection
Zambrano LD, Ly KN, Link-Gelles R, Newhams MM, Akande M, Wu MJ, Feldstein LR, Tarquinio KM, Sahni LC, Riggs BJ, Singh AR, Fitzgerald JC, Schuster JE, Giuliano JS, Englund JA, Hume JR, Hall MW, Osborne CM, Doymaz S, Rowan CM, Babbitt CJ, Clouser KN, Horwitz SM, Chou J, Patel MM, Hobbs C, Randolph AG, Campbell AP, Investigators F. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. The Pediatric Infectious Disease Journal 2022, 41: 891-898. PMID: 36102740, PMCID: PMC9555608, DOI: 10.1097/inf.0000000000003689.Peer-Reviewed Original ResearchConceptsMIS-C casesNon-Hispanic black childrenInflammatory syndromeRisk factorsMedical conditionsMixed-effects multivariable logistic regressionSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2SARS-CoV-2 infectionRespiratory syndrome coronavirus 2MIS-C patientsMultisystem inflammatory syndromeUnderlying medical conditionsMultivariable logistic regressionSyndrome coronavirus 2Case-control studyNon-Hispanic blacksBlack childrenMultivariable analysisPediatric hospitalCoronavirus 2Insurance statusIndependent factorsSimilar sexSocial Vulnerability IndexLife-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children
Halasa NB, Spieker AJ, Young CC, Olson SM, Newhams MM, Amarin JZ, Moffitt KL, Nakamura MM, Levy ER, Soma VL, Talj R, Weiss SL, Fitzgerald JC, Mack EH, Maddux AB, Schuster JE, Coates BM, Hall MW, Schwartz SP, Schwarz AJ, Kong M, Spinella PC, Loftis LL, McLaughlin GE, Hobbs CV, Rowan CM, Bembea MM, Nofziger RA, Babbitt CJ, Bowens C, Flori HR, Gertz SJ, Zinter MS, Giuliano JS, Hume JR, Cvijanovich NZ, Singh AR, Crandall HA, Thomas NJ, Cullimore ML, Patel MM, Randolph AG, Kong M, Gaspers M, Typpo K, Sanders R, Katherine I, Peter M, Schwarz A, Babbitt C, Helen H, Cvijanovich N, Zinter M, Maddux A, Osborne C, Sara S, Mourani P, Emily P, Van K, Carroll C, Giuliano J, McLaughlin G, Tarquinio K, Michelson K, Coates B, Rowan C, Wellnitz K, Bhoojhawon, Sullivan J, Montgomery V, Havlin K, Bradford T, Riggs B, Bembea M, Randolph A, Newhams M, Chen S, Young C, Moffitt K, Nakamura M, Carroll R, Yager P, Fernandes N, Flori H, Heidemann S, Hume J, Levy E, Hobbs C, Martin L, Malloch L, Inagaki K, Dhanrajani A, Schuster J, Kietzman A, Hill S, Spinella P, Cullimore M, McCulloh R, Clouser K, Gertz S, Kleinman L, Li S, Horwitz S, Ratner A, Dapul H, Soma V, Keenaghan M, Singh A, Harwayne-Gidansky I, Hymes S, Doymaz S, Schwartz S, Walker T, Hall M, Shein S, Lansell A, Nofziger R, Staat M, Fitzgerald J, Weiss S, Thomas N, Fink E, Carcillo J, Mack E, Smallcomb L, Halasa N, Stewart L, Romero Y, Hayek H, Loftis L, Munoz A, Bowens C, Maamari M, Crandall H, Smith L, McGuire J. Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children. Clinical Infectious Diseases 2022, 76: ciac477. PMID: 35717646, PMCID: PMC9384330, DOI: 10.1093/cid/ciac477.Peer-Reviewed Original ResearchConceptsLife-threatening complicationsOdds of deathCoronavirus disease 2019Clinical characteristicsDisease 2019COVID-19US childrenLife supportHigher-acuity unitsInvasive mechanical ventilationShorter hospital stayNon-Hispanic blacksVasopressor supportHospital stayCritical illnessMembrane oxygenationPediatric patientsInfluenza infectionMechanical ventilationIntensive careClinical differencesUnderlying conditionDisease severityInfluenzaMixed-effects models