High level expression of fms proto-oncogene mRNA is observed in clinically aggressive human endometrial adenocarcinomas
Kacinski B, Carter D, Mittal K, Kohorn E, Bloodgood R, Donahue J, Donofrio L, Edwards R, Schwartz P, Chambers J, Chambers S. High level expression of fms proto-oncogene mRNA is observed in clinically aggressive human endometrial adenocarcinomas. International Journal Of Radiation Oncology • Biology • Physics 1988, 15: 823-829. PMID: 3182322, DOI: 10.1016/0360-3016(88)90113-7.Peer-Reviewed Original ResearchConceptsEndometrial currettingsDeep myometrial penetrationStage I patientsAggressive clinical behaviorHuman endometrial adenocarcinomaMicron paraffin sectionsMyometrial penetrationLocoregional spreadClinicopathologic featuresEndometrial adenocarcinomaI patientsPoor outcomeEndometrial specimensClinical behaviorInvasive adenocarcinomaBenign hyperplasiaAdenocarcinomaMalignant phenotypeParaffin sectionsM-CSFM-CSF receptorOncogene expressionProto-oncogene mRNAKi-rasPatients