Oxidative Addition of the Dithiobis(formamidinium) Cation to Platinum(II) Chloro Am(m)ine Compounds: Studies on Structure, Spectroscopic Properties, Reactivity, and Cytotoxicity of a New Class of Platinum(IV) Complexes Exhibiting S-Thiourea Coordination
Bierbach U, Hambley TW, Roberts JD, Farrell N. Oxidative Addition of the Dithiobis(formamidinium) Cation to Platinum(II) Chloro Am(m)ine Compounds: Studies on Structure, Spectroscopic Properties, Reactivity, and Cytotoxicity of a New Class of Platinum(IV) Complexes Exhibiting S-Thiourea Coordination. Inorganic Chemistry 1996, 35: 4865-4872. PMID: 11666686, DOI: 10.1021/ic960314g.Peer-Reviewed Original ResearchTrans influenceOxidative additionSingle-crystal X-ray structureS-donor ligandsPronounced trans influencePt–Cl bondsX-ray structureSpace group C2/Chloro ligandsUnusual acidityUpfield shiftSpectroscopic propertiesElectrode measurementsL1210 cell lineCarrier ligandLigand combinationsTrans additionYields cisTMTULigandsSpace groupTrans isomerizationC2/Cellular uptakeOxidation