1998
Modification of Platinum(II) Antitumor Complexes with Sulfur Ligands. 2. Reactivity and Nucleotide Binding Properties of Cationic Complexes of the Types [PtCl(diamine)(L)]NO3 and [{PtCl(diamine)}2(L-L)](NO3)2 (L = Monofunctional Thiourea Derivative; L-L = Bifunctional Thiourea Derivative) in Relation to Their Cytotoxicity
Bierbach U, Roberts J, Farrell N. Modification of Platinum(II) Antitumor Complexes with Sulfur Ligands. 2. Reactivity and Nucleotide Binding Properties of Cationic Complexes of the Types [PtCl(diamine)(L)]NO3 and [{PtCl(diamine)}2(L-L)](NO3)2 (L = Monofunctional Thiourea Derivative; L-L = Bifunctional Thiourea Derivative) in Relation to Their Cytotoxicity. Inorganic Chemistry 1998, 37: 717-723. DOI: 10.1021/ic970421q.Peer-Reviewed Original ResearchAntitumor complexesAqueous solution chemistryDinuclear complexes 3Dinuclear compound 3NMR chemical shiftsN-type conformationComplexes 3Thiourea ligandsCationic complexesSulfur ligandsNMR spectroscopyChemical shiftsSolution chemistryDinuclear adductsIntramolecular disproportionationAnalogous reactionCompound 3Aqueous solutionMonofunctional adductsBifunctional adductsRate of hydrolysisAdductsBinding propertiesChemistryCytotoxicity data
1989
Interaction of novel bis(platinum) complexes with DNA
Roberts J, Van Houten B, Qu Y, Farrell N. Interaction of novel bis(platinum) complexes with DNA. Nucleic Acids Research 1989, 17: 9719-9733. PMID: 2690006, PMCID: PMC335209, DOI: 10.1093/nar/17.23.9719.Peer-Reviewed Original Research