2024
Clinical Interviewing: An Essential but Neglected Method of Medicine
Fava G, Sonino N, Aron D, Balon R, Montiel C, Cao J, Concato J, Eory A, Horwitz R, Rafanelli C, Schnyder U, Wang H, Wise T, Wright J, Zipfel S, Patierno C. Clinical Interviewing: An Essential but Neglected Method of Medicine. Psychotherapy And Psychosomatics 2024, 93: 94-99. PMID: 38382481, DOI: 10.1159/000536490.Peer-Reviewed Original ResearchClinical interviewIncrease patient motivationHealthy behaviorsMethods of medicineSelf-managementClinical encountersPatient motivationClinical processesPatient informationQuality of interviewsEducational trainingLack cost effectivenessClinical domainsPresenting complaintMedical historyInterviewsPhysiciansLife settingsTime pressureQuality of dataPersonal attitudesPatientsCost-effectiveExpensive testsDecision making
2013
Study Design and “Evidence” in Patient-oriented Research
Concato J. Study Design and “Evidence” in Patient-oriented Research. American Journal Of Respiratory And Critical Care Medicine 2013, 187: 1167-1172. PMID: 23725613, DOI: 10.1164/rccm.201303-0521oe.Peer-Reviewed Original ResearchConceptsRandomized trialsObservational studyPatient-oriented researchStudy designCritical care literatureEvidence-based medicineGeneral medicalCause-effect associationClinical careGold standard statusComparative effectivenessEvidence baseTrialsCare literatureIndividual studiesPatientsStudy resultsResearch designStudyMethodological designCareEvidence approach
2010
Observational Methods in Comparative Effectiveness Research
Concato J, Lawler EV, Lew RA, Gaziano JM, Aslan M, Huang GD. Observational Methods in Comparative Effectiveness Research. The American Journal Of Medicine 2010, 123: e16-e23. PMID: 21184862, DOI: 10.1016/j.amjmed.2010.10.004.Peer-Reviewed Original ResearchConceptsComparative effectiveness researchObservational studyGroup of patientsVeterans Health AdministrationEffectiveness researchSpecific medical conditionsPatient-oriented researchCorresponding study designPatient populationTreatment optionsMedical conditionsHealth AdministrationStudy designMedical ailmentsIndividual studiesAvailable optionsPatientsRCTsOptionsProminent featureStudyAdministrationTrials
2006
The Effectiveness of Screening for Prostate Cancer: A Nested Case-Control Study
Concato J, Wells CK, Horwitz RI, Penson D, Fincke G, Berlowitz DR, Froehlich G, Blake D, Vickers MA, Gehr GA, Raheb NH, Sullivan G, Peduzzi P. The Effectiveness of Screening for Prostate Cancer: A Nested Case-Control Study. JAMA Internal Medicine 2006, 166: 38-43. PMID: 16401808, DOI: 10.1001/archinte.166.1.38.Peer-Reviewed Original ResearchConceptsDigital rectal examinationCase-control studyCause-specific mortalityCase patientsProstate cancerControl patientsNested Case-Control StudyProstate-specific antigen (PSA) testVeterans Affairs Medical CenterAssociation of screeningBenefits of screeningEffectiveness of screeningVeterans Affairs facilitiesVerbal informed consentEffectiveness of PSADRE screeningCause mortalityPSA testingSurvival benefitRectal examinationAntigen testMedical CenterAmbulatory carePatientsClinical practice
2002
Factors associated with caregiver burden among caregivers of patients with cancer in a hospice setting
Goldstein N, Concato J, Fried T, Cherlin E, Kasl S, Bradley E. Factors associated with caregiver burden among caregivers of patients with cancer in a hospice setting. Journal Of Clinical Epidemiology 2002, 55: 628. DOI: 10.1016/s0895-4356(02)00418-3.Peer-Reviewed Original ResearchCaregivers of patientsCaregiver burdenSocio-demographic characteristicsSocial Network IndexCaregivers' socio-demographic characteristicsSelf-reported health statusZarit Burden InventoryLevel of burdenCross-sectional surveyBurden scoreBurden InventoryChronic illnessSummary scoresHospice settingsCaregivers' perceptionsHealth statusWorse scoresYounger ageCaregivers' feelingsGreater burdenLogistic regressionUpper quartilePrimary caregiversPatientsCaregiversCoping strategies and their associations with levels of disability or pain, among older veterans receiving primary care
Reid M, Barry L, Kerns R, Duong B, Concato J. Coping strategies and their associations with levels of disability or pain, among older veterans receiving primary care. Journal Of Clinical Epidemiology 2002, 55: 629. DOI: 10.1016/s0895-4356(02)00420-1.Peer-Reviewed Original ResearchChronic non-cancer painNon-cancer painLevel of disabilityChronic painSelf-reported effectivenessOlder personsPrimary careOlder veteransMedication usePain intensityComorbid conditionsMean ageCoping strategiesPainEligibility criteriaPsychological statusMultivariate analysisTelephone interviewsCold modalitiesLow levelsEligibility statusDisabilityReduced levelsPatientsPositive associationWhat is “biochemical failure” in prostate cancer?
Lagu T, Wells C, Penson D, Concato J. What is “biochemical failure” in prostate cancer? Journal Of Clinical Epidemiology 2002, 55: 631. DOI: 10.1016/s0895-4356(02)00425-0.Peer-Reviewed Original ResearchProstate-specific antigenPSA failureMedian timeType of treatmentPSA slopeProstate cancerPost-treatment prostate-specific antigenVeterans Affairs Healthcare SystemAge-matched menProportion of menBiochemical failureSurgical failureTreatment failureSurrogate endpointsTherapeutic radiationAbility of providersVA sitesActual therapyPatientsClinical phenomenaCancerKappa statisticsHealthcare systemMenAmerican Society
2001
Risk adjustment for older hospitalized persons A comparison of two methods of data collection for the Charlson index
van Doorn C, Bogardus S, Williams C, Concato J, Towle V, Inouye S. Risk adjustment for older hospitalized persons A comparison of two methods of data collection for the Charlson index. Journal Of Clinical Epidemiology 2001, 54: 694-701. PMID: 11438410, DOI: 10.1016/s0895-4356(00)00367-x.Peer-Reviewed Original ResearchConceptsICD-9 dataCharlson indexMortality predictionComorbid conditionsOlder general medical patientsYale-New Haven HospitalRisk adjustmentOriginal Charlson indexSpecific comorbid conditionsGeneral medical patientsGeneral medicine wardsHospital admission dateCharlson scoreIndividual comorbiditiesConsecutive patientsMedicine wardsClinical evidenceMedical patientsAdmission dateChart-based dataMortality riskICD-9PatientsChart dataLow agreementPreference for disclosure of information among patients with rheumatoid arthritis
Fraenkel L, Bogardus S, Concato J, Felson D. Preference for disclosure of information among patients with rheumatoid arthritis. Arthritis & Rheumatism 2001, 45: 136-139. PMID: 11324776, DOI: 10.1002/1529-0131(200104)45:2<136::aid-anr165>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisRA patientsSex-specific analysesSex-specific correlatesInformation preferencesPatient characteristicsTherapeutic optionsFemale sexSide effectsPatientsBivariate analysisHigher education levelCurrent employmentArthritisMean scoreEducation levelAlternative optionRiskFull disclosureOptionsMultiple linear regressionLinear regressionStepwise multiple linear regressionMedicationsRheumatologists
2000
Treatment Decisions for Localized Prostate Cancer
Holmboe E, Concato J. Treatment Decisions for Localized Prostate Cancer. Journal Of General Internal Medicine 2000, 15: 694-701. PMID: 11089712, PMCID: PMC1495597, DOI: 10.1046/j.1525-1497.2000.90842.x.Peer-Reviewed Original ResearchConceptsExternal beam radiationLocalized prostate cancerWatchful waitingProstate cancerRadical prostatectomyTreatment optionsTreatment decisionsCommon reasonPattern of complicationsPrimary care providersRemoval of tumorsLack of evidencePhysician recommendationConsecutive menCare providersHigh riskPatient decisionCancerLonger durationPractice groupMenBeam radiationTreatmentPatientsShort durationBeyond Diagnosis: Patient Mix and Challenges to Patient Care in Ambulatory Training Sites
Fiellin D, Concato J. Beyond Diagnosis: Patient Mix and Challenges to Patient Care in Ambulatory Training Sites. The American Journal Of The Medical Sciences 2000, 319: 106. PMID: 10698095, DOI: 10.1097/00000441-200002000-00007.Peer-Reviewed Original ResearchConceptsPrimary care centersAmbulatory training sitesPatient mixPatient-physician communicationVA Medical CenterCommon medical diagnosesInternal medicine residentsVA subjectsComorbidity scoreCare centerMedical CenterHealth statusPatient carePatient spectrumAmbulatory trainingPatientsMedicine residentsDiagnosisGroup practiceAmbulatory medicineCareTraining sitesMedical decisionsVA
1998
Physician Awareness of Alcohol Use Disorders Among Older Patients
Reid M, Tinetti M, Brown C, Concato J. Physician Awareness of Alcohol Use Disorders Among Older Patients. Journal Of General Internal Medicine 1998, 13: 729-734. PMID: 9824517, PMCID: PMC1497030, DOI: 10.1046/j.1525-1497.1998.00223.x.Peer-Reviewed Original ResearchConceptsAlcohol use disorderOlder patientsPrimary care physiciansInternal medicine physiciansCare physiciansPhysician awarenessMedicine physiciansUse disordersPrevalence estimatesPrimary care physicians' awarenessAnnual screening ratesQuantity-frequency questionsCross-sectional telephone surveyFamily practice physiciansGroup of physiciansCAGE questionsScreening ratesRegular screeningMiddle-aged physiciansPrevalence ratesPractice physiciansPhysician educationPatientsOlder physiciansBiochemical markers
1997
Asking Patients What They Like: Overlooked Attributes of Patient Satisfaction with Primary Care
Concato J, Feinstein A. Asking Patients What They Like: Overlooked Attributes of Patient Satisfaction with Primary Care. The American Journal Of Medicine 1997, 102: 399-406. PMID: 9217623, DOI: 10.1016/s0002-9343(97)00092-2.Peer-Reviewed Original ResearchConceptsPatient satisfactionVeterans Affairs Medical CenterPrimary care clinicsPrimary health careHealth care servicesClinic visitsCare clinicsSame clinicOpen-ended questionsPrimary careClinimetric methodsMedical CenterPatientsCare servicesPhysician staffNonphysician staffClinicHealth careCareFace validityPsychometric instrumentsResponseSatisfactionCliniciansStaff
1996
Importance of cerebrovascular disease in studies of myocardial infarction.
Brass L, Hartigan P, Page W, Concato J. Importance of cerebrovascular disease in studies of myocardial infarction. Stroke 1996, 27: 1173-6. PMID: 8685923.Peer-Reviewed Original ResearchConceptsRate of strokeIschemic heart diseaseMyocardial infarctionHeart diseaseMonozygotic twinsManifestations of atherosclerosisWhite male veteransTwin pairsComplete responseTherapeutic trialsCerebrovascular diseaseHigh riskPrognostic studiesClinical investigationInfarctionMale veteransStrokeTwin RegistryStrong associationDiseaseOverall rateAtherosclerosisPatientsRegistryEnvironmental factorsFactors associated with successful implantation of nonthoracotomy defibrillation lead systems
Schwartzman D, Concato J, Ren J, Callans D, Gottlieb C, Preminger M, Marchlinski F. Factors associated with successful implantation of nonthoracotomy defibrillation lead systems. American Heart Journal 1996, 131: 1127-1136. PMID: 8644591, DOI: 10.1016/s0002-8703(96)90087-3.Peer-Reviewed Original ResearchConceptsNonthoracotomy defibrillation lead systemsDefibrillation lead systemsClinical factorsDefibrillation thresholdImplantation failureBiphasic shock waveformLead-related factorsShock waveformHigh defibrillation thresholdMonophasic shock waveformsLower defibrillation thresholdLead systemMonophasic groupConsecutive patientsBiphasic groupIncidence of successEndovascular SystemPatientsSuccessful implantationIncidenceImplantationFailureFactorsGroup
1995
Sex differences in the management of patients hospitalized with ischemic cerebrovascular disease.
Patrick S, Concato J, Viscoli C, Chyatte D, Brass L. Sex differences in the management of patients hospitalized with ischemic cerebrovascular disease. Stroke 1995, 26: 577-80. PMID: 7709400, DOI: 10.1161/01.str.26.4.577.Peer-Reviewed Original ResearchConceptsAge-adjusted odds ratioIschemic cerebrovascular diseaseArtery diseaseCerebrovascular diseaseOdds ratioCoronary artery diseaseManagement of patientsCarotid artery diseaseUse of angiographyAge-adjusted ratesSex differencesCerebral angiographyCarotid diseaseMale patientsCarotid endarterectomyConnecticut hospitalsEndarterectomyDisease typePatientsAngiographyDiseaseWomenMenBiological differencesSex
1993
Therapies for Benign Prostatic Hyperplasia
Concato J, Horwitz R, Feinstein A, Elmore J, Schiff S. Therapies for Benign Prostatic Hyperplasia. JAMA 1993, 269: 867-867. PMID: 7678874, DOI: 10.1001/jama.1993.03500070047017.Peer-Reviewed Original ResearchConceptsBenign prostatic hyperplasiaProstatic hyperplasiaOpen prostatectomyHigh mortalityYale-New Haven HospitalSurvival of patientsTime of surgeryT-testStudent's t-testTransurethral resectionTrial investigatorsTURPMortalityHyperplasiaPatientsProstatectomyResectionSurgeryHospitalTherapyProstateTrials
1992
Therapies for Benign Prostatic Hyperplasia-Reply
Concato J, Horwitz R, Feinstein A, Elmore J, Schiff S. Therapies for Benign Prostatic Hyperplasia-Reply. JAMA 1992, 268: 1269-1269. DOI: 10.1001/jama.1992.03490100063026.Peer-Reviewed Original ResearchProblems of Comorbidity in Mortality After Prostatectomy
Concato J, Horwitz R, Feinstein A, Elmore J, Schiff S. Problems of Comorbidity in Mortality After Prostatectomy. JAMA 1992, 267: 1077-1082. PMID: 1370963, DOI: 10.1001/jama.1992.03480080047025.Peer-Reviewed Original ResearchConceptsBenign prostatic hyperplasiaLong-term mortalityTime of surgeryTreatment of BPHOpen prostatectomyTURP groupOpen groupHigher long-term mortalityYale-New Haven HospitalClassifications of comorbidityRetrospective cohort studyFive-year mortalityAssessment of comorbiditiesSeverity of illnessProblem of comorbidityAdjusted riskComorbid illnessesCohort studyTransurethral resectionProstatic hyperplasiaPatient outcomesMortality ratePatientsProstatectomyHigh mortality