2024
Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis.
Trujillo G, Regueiro-Ren A, Liu C, Hu B, Sun Y, Ahangari F, Fiorini V, Ishikawa G, Al Jumaily K, Khoury J, McGovern J, Lee C, Peng X, Pivarnik T, Sun H, Walia A, Woo S, Yu S, Antin-Ozerkis D, Sauler M, Kaminski N, Herzog E, Ryu C. Toll-like Receptor 9 Inhibition Mitigates Fibroproliferative Responses in Translational Models of Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024 PMID: 39189851, DOI: 10.1164/rccm.202401-0065oc.Peer-Reviewed Original ResearchToll-like receptor 9Model of pulmonary fibrosisIdiopathic pulmonary fibrosisPulmonary fibrosisFibroproliferative responseLung diseaseIdiopathic pulmonary fibrosis cohortsExpression of toll-like receptor 9Toll-like receptor 9 activationTransplant-free survivalExpression of MCP-1Cohort of patientsSlow clinical progressionFibrotic lung diseaseAccelerated disease courseFatal lung diseaseIP-10Pharmacodynamic endpointsPreclinical modelsDisease courseClinical progressionPlasma mtDNAMCP-1Receptor 9Mouse model
2020
ERS International Congress, Madrid, 2019: highlights from the Pulmonary Vascular Diseases Assembly
Ramjug S, Weatherald J, Sahay S, Khoury J, Foris V, Chandran N, Bokan A, Godinas L, Delcroix M. ERS International Congress, Madrid, 2019: highlights from the Pulmonary Vascular Diseases Assembly. ERJ Open Research 2020, 6: 00304-2020. PMID: 33083438, PMCID: PMC7553109, DOI: 10.1183/23120541.00304-2020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPulmonary arterial hypertensionAcute pulmonary embolismPulmonary hypertensionPulmonary embolismRisk stratificationLung diseaseEuropean Respiratory Society International CongressPulmonary vascular diseaseInterstitial lung diseaseERS International CongressESC guidelinesArterial hypertensionCardiology guidelinesPrognostic factorsVascular diseasePotential therapyFuture therapiesHypertensionNoninvasive measurePotential biomarkersRespiratory communityExciting sessionEuropean SocietyDiseaseScientific Session