2013
Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults
White S, Acierno R, Ruggiero KJ, Koenen KC, Kilpatrick DG, Galea S, Gelernter J, Williamson V, McMichael O, Vladimirov VI, Amstadter AB. Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults. Journal Of Anxiety Disorders 2013, 27: 678-683. PMID: 24077033, PMCID: PMC4182958, DOI: 10.1016/j.janxdis.2013.08.003.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPTSD symptomsHormone receptor 1 geneCorticotropin-releasing hormone receptor 1 (CRHR1) geneSingle nucleotide polymorphismsReceptor 1 geneCRHR1 variationEtiology of PTSDHPA axisAdrenal axisCRHR1 variantsPosttraumatic stress symptomsStress disorderAnxiety disordersFinal analysisSymptomsHeritable anxiety disordersEuropean-American subsampleAdultsStress symptomsCRHR1Genetic variantsMultiple testingDiagnosisDisorders
2001
Linkage genome scan for loci predisposing to panic disorder or agoraphobia
Gelernter J, Bonvicini K, Page G, Woods S, Goddard A, Kruger S, Pauls D, Goodson S. Linkage genome scan for loci predisposing to panic disorder or agoraphobia. American Journal Of Medical Genetics 2001, 105: 548-557. PMID: 11496373, DOI: 10.1002/ajmg.1496.Peer-Reviewed Original ResearchMeSH KeywordsAgoraphobiaChromosome MappingChromosomes, Human, Pair 1Chromosomes, Human, Pair 11Chromosomes, Human, Pair 14Chromosomes, Human, Pair 3Chromosomes, Human, Pair 4Family HealthFemaleGenetic Predisposition to DiseaseGenome, HumanHumansLod ScoreMaleMicrosatellite RepeatsPanic DisorderPedigreeConceptsLinkage genome scanGenome scanChromosome 3LOD scoreSuggestive linkagePrevious genome scanComplex traitsGenomic regionsHeritable anxiety disordersGenetic lociMultipoint LOD scoreCandidate genesRisk lociChromosome 1Chromosome 11pSusceptibility lociLociStatistical supportLinkage resultsNPL analysisPotential lociNPL scoreAmerican pedigreesSingle familyPotential linkage