2014
Clinical features of methamphetamine‐induced paranoia and preliminary genetic association with DBH‐1021C→T in a Thai treatment cohort
Kalayasiri R, Verachai V, Gelernter J, Mutirangura A, Malison RT. Clinical features of methamphetamine‐induced paranoia and preliminary genetic association with DBH‐1021C→T in a Thai treatment cohort. Addiction 2014, 109: 965-976. PMID: 24521142, PMCID: PMC4018411, DOI: 10.1111/add.12512.Peer-Reviewed Original ResearchConceptsDopamine β-hydroxylaseMethamphetamine-dependent individualsAssociated clinical variablesGenetic polymorphismsΒ-hydroxylaseLogistic regression analysisSubstance abuse treatment centersHigh-activity genotypesSemi-Structured AssessmentAntisocial personality disorderCT carriersCent of individualsClinical featuresClinical presentationCigarette smokingClinical variablesRetrospective analysisTreatment centersDrug dependenceActivity genotypeMethamphetamine useMethamphetamine dependencePersonality disorderRegression analysisGenetic association
2002
Molecular Genetic Analysis of Plasma Dopamine β-Hydroxylase in Depression
Cubells J, Zabetian C, Anderson G, Price L, Meyers B, Malison R, Nelson J, Nagatsu T, Ichinose H, Gelernter J. Molecular Genetic Analysis of Plasma Dopamine β-Hydroxylase in Depression. Advances In Behavioral Biology 2002, 53: 423-426. DOI: 10.1007/978-1-4757-3538-3_101.Peer-Reviewed Original ResearchDβH proteinEnzyme activityMolecular genetic analysisBiochemical traitsGenetic analysisMajor locusNeurosecretory vesiclesGenetic inheritanceΒ-hydroxylaseDopamine β-hydroxylaseTraitsNeurosecretory cellsProteinDβH levelsConversion of dopamineLociVesiclesPlasma dopamine β-hydroxylaseInheritanceMembraneActivityCells