Recent advances in MS methods for nicotine and metabolite analysis in human matrices: clinical perspectives
El-Khoury JM, Wang S. Recent advances in MS methods for nicotine and metabolite analysis in human matrices: clinical perspectives. Bioanalysis 2014, 6: 2171-2183. PMID: 25331861, DOI: 10.4155/bio.14.176.Peer-Reviewed Original ResearchConceptsHuman matricesMajor global health issueSecond-hand exposureGlobal health issueTobacco smokingPreventable deathsTobacco consumptionAppropriate biomarkersHand exposureClinical MSNicotine metabolismClinical perspectiveTobacco productsHealth issuesNicotineMeasurement of nicotineMetabolitesStandard reference methodDetection of nicotineSmokingMetabolite analysisBiomarkersSuperior sensitivity