Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.
Lerner EA, Lerner MR, Janeway CA, Steitz JA. Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 1981, 78: 2737-2741. PMID: 6789322, PMCID: PMC319432, DOI: 10.1073/pnas.78.5.2737.Peer-Reviewed Original ResearchConceptsAnti-Sm antibodiesMonoclonal anti-Sm antibodyAutoimmune diseasesMonoclonal antibodiesLupus erythematosus-like syndromeMRL/Mp-lpr/lprProduction of autoantibodiesPatient seraSpleen cellsImmunofluorescence techniqueAntibodiesSP 2/0Competition radioimmunoassayImmunoprecipitation patternsCell linesSm antigenAntigenDiseaseMiceCellular constituentsCellular componentsAutoantibodiesPatientsLupusSyndrome