1995
ENHANCED PERSPECTIVE: Small RNA Chaperones for Ribosome Biogenesis
Steitz J, Tycowski K. ENHANCED PERSPECTIVE: Small RNA Chaperones for Ribosome Biogenesis. Science 1995, 270: 1626-1626. PMID: 7502072, DOI: 10.1126/science.270.5242.1626.Peer-Reviewed Original Research
1994
Organization of small nucleolar ribonucleoproteins (snoRNPs) by fluorescence in situ hybridization and immunocytochemistry.
Matera AG, Tycowski KT, Steitz JA, Ward DC. Organization of small nucleolar ribonucleoproteins (snoRNPs) by fluorescence in situ hybridization and immunocytochemistry. Molecular Biology Of The Cell 1994, 5: 1289-1299. PMID: 7535131, PMCID: PMC301158, DOI: 10.1091/mbc.5.12.1289.Peer-Reviewed Original Research
1992
A new interaction between the mouse 5′ external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking
Tyc K, Steitz J. A new interaction between the mouse 5′ external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking. Nucleic Acids Research 1992, 20: 5375-5382. PMID: 1437554, PMCID: PMC334344, DOI: 10.1093/nar/20.20.5375.Peer-Reviewed Original Research
1991
Three pseudogenes for human U13 snRNA belong to class III
Baserga S, Yang X, Steitz J. Three pseudogenes for human U13 snRNA belong to class III. Gene 1991, 107: 347-348. PMID: 1748306, DOI: 10.1016/0378-1119(91)90340-h.Peer-Reviewed Original Research
1988
An in vitro interaction between the human U3 snRNP and 28S rRNA sequences near the α-sarcin site
Parker K, Bruzik J, Steitz J. An in vitro interaction between the human U3 snRNP and 28S rRNA sequences near the α-sarcin site. Nucleic Acids Research 1988, 16: 10493-10509. PMID: 2974535, PMCID: PMC338920, DOI: 10.1093/nar/16.22.10493.Peer-Reviewed Original ResearchAntibodiesBase CompositionBase SequenceEndoribonucleasesFungal ProteinsHeLa CellsHumansMolecular Sequence DataNucleic Acid ConformationPlasmidsProtein Synthesis InhibitorsRibonuclease T1RibonucleoproteinsRibonucleoproteins, Small NuclearRNA PrecursorsRNA, RibosomalRNA, Ribosomal, 28STranscription, GeneticA 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells.
Steitz JA, Berg C, Hendrick JP, La Branche-Chabot H, Metspalu A, Rinke J, Yario T. A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells. Journal Of Cell Biology 1988, 106: 545-556. PMID: 3279045, PMCID: PMC2115095, DOI: 10.1083/jcb.106.3.545.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoantibodiesCell NucleolusCentrifugation, Density GradientElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueFriend murine leukemia virusHeLa CellsHumansImmunoassayLeukemia, Erythroblastic, AcuteRibonucleoproteinsRibosomal ProteinsRibosomesRNA PrecursorsRNA, RibosomalRNA, Ribosomal, 5STumor Cells, CulturedConceptsRNA-protein complexesVivo pulse-chase experimentsRibosomal protein L5Pulse-chase experimentsProtein complexesProtein L5Mammalian cellsRNA moleculesMouse cellsLater stepsHeLa cellsProtein moietyRNPRibosomesNucleoliCellsComplexesAssemblyBiogenesisRRNAIndirect immunofluorescenceSubunitsRNAImmunofluorescence
1987
Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes.
Chabot B, Steitz JA. Multiple interactions between the splicing substrate and small nuclear ribonucleoproteins in spliceosomes. Molecular And Cellular Biology 1987, 7: 281-293. PMID: 2951586, PMCID: PMC365068, DOI: 10.1128/mcb.7.1.281.Peer-Reviewed Original Research
1982
Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La Lupus antibodies
Rinke J, Steitz J. Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La Lupus antibodies. Cell 1982, 29: 149-159. PMID: 7105180, DOI: 10.1016/0092-8674(82)90099-x.Peer-Reviewed Original ResearchConceptsRRNA moleculesLa proteinLa RNAsPrecursor formNuclear transcription systemUninfected mammalian cellsPulse-chase experimentsSmall RNAsSmall ribonucleoproteinPrecursor moleculesTransfer RNAMammalian cellsRibosomal RNATRNA precursorsCertain tRNAsSpecific tRNAsRNA transcriptsTranscription systemU residuesCell extractsMature sizeHeLa cellsRNAEssential roleProtein
1980
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli
Bram R, Young R, Steitz J. The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell 1980, 19: 393-401. PMID: 6153577, DOI: 10.1016/0092-8674(80)90513-9.Peer-Reviewed Original Research
1979
Tandem promoters direct E. coli ribosomal RNA synthesis
Young R, Steitz J. Tandem promoters direct E. coli ribosomal RNA synthesis. Cell 1979, 17: 225-234. PMID: 110460, DOI: 10.1016/0092-8674(79)90310-6.Peer-Reviewed Original ResearchThe 3′ terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1
Yuan R, Steitz J, Moore P, Crothers D. The 3′ terminus of 16S rRNA: secondary structure and interaction with ribosomal protein S1. Nucleic Acids Research 1979, 7: 2399-2418. PMID: 392471, PMCID: PMC342392, DOI: 10.1093/nar/7.8.2399.Peer-Reviewed Original Research
1978
Methanogenic bacteria
STEITZ J. Methanogenic bacteria. Nature 1978, 273: 10-10. PMID: 692664, DOI: 10.1038/273010a0.Peer-Reviewed Original ResearchConservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells
Hagenbüchle O, Santer M, Steitz J, Mans R. Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells. Cell 1978, 13: 551-563. PMID: 77738, DOI: 10.1016/0092-8674(78)90328-8.Peer-Reviewed Original ResearchConceptsE. coli 16S rRNAE. coli ribosomesPurine-rich regionDNA sequencing methodsRRNA moleculesEucaryotic speciesStrong homologyCDNA transcriptsCDNA copyPolynucleotidyl transferasesRNA moleculesRRNA sequencesEucaryotic cellsEucaryotic mRNAsExtensive complementarityColi ribosomesRRNAPrimary structureEnzyme ATPSequencing methodsOligonucleotide primersAMV reverse transcriptaseTerminusReverse transcriptaseSequence
1977
Characterization of two mRNA · rRNA complexes implicated in the initiation of protein biosynthesis
Steitz J, Steege D. Characterization of two mRNA · rRNA complexes implicated in the initiation of protein biosynthesis. Journal Of Molecular Biology 1977, 114: 545-558. PMID: 335077, DOI: 10.1016/0022-2836(77)90177-2.Peer-Reviewed Original ResearchConceptsProtein biosynthesisEscherichia coli 16 S ribosomal RNAS ribosomal RNABase pair regionNuclease digestion studiesFragment complexAssignment of residuesRibosomal RNARRNA complexLambda PRBacteriophage lambdaMolecular understandingInitiation siteInitiation eventsStrong experimental supportMessenger RNABiosynthesisThermal denaturation studiesDenaturation studiesRNAPR transcriptsPR regionDigestion studiesMRNAComplexes3′ Terminal sequences of 16S rRNA do not explain translational specificity differences between E. coli and B. stearothermophilus ribosomes
SPRAGUE KU, STEITZ JA, GRENLEY RM, STOCKING CE. 3′ Terminal sequences of 16S rRNA do not explain translational specificity differences between E. coli and B. stearothermophilus ribosomes. Nature 1977, 267: 462-465. PMID: 327330, DOI: 10.1038/267462a0.Peer-Reviewed Original Research
1975
The 3′ terminal oligonucleotide of E.coli 16S ribosomal RNA: the sequence in both wild-type and RNase III cells is complementary to the polypurine tracts common to mRNA initiator regions
Sprague K, Steitz J. The 3′ terminal oligonucleotide of E.coli 16S ribosomal RNA: the sequence in both wild-type and RNase III cells is complementary to the polypurine tracts common to mRNA initiator regions. Nucleic Acids Research 1975, 2: 787-798. PMID: 167351, PMCID: PMC343466, DOI: 10.1093/nar/2.6.787.Peer-Reviewed Original Research