2023
Arterial spin labeled perfusion imaging with balanced steady-state free precession readout and radial sampling
Han P, Marin T, Zhuo Y, Ouyang J, El Fakhri G, Ma C. Arterial spin labeled perfusion imaging with balanced steady-state free precession readout and radial sampling. Magnetic Resonance Imaging 2023, 102: 126-132. PMID: 37187264, PMCID: PMC10524790, DOI: 10.1016/j.mri.2023.05.005.Peer-Reviewed Original ResearchMeSH KeywordsArteriesBrainImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingPerfusionPerfusion ImagingSpin LabelsConceptsOff-resonance effectsBalanced steady-state free precessionPhase-cycling techniqueTemporal SNRBalanced steady-state free precession acquisitionRadial sampling schemeSpoiled gradient-recalled acquisitionRadial samplingCartesian sampling schemeBalanced steady-state free precession readoutK-space dataSampling schemeSpin labelingSteady-state free precessionK-spaceImage readoutBanding artifactsMotion-related artifactsReadoutFree precessionArterial spin labelingImage reconstructionParallel imagingImaging timePerfusion-weighted imaging
2020
Motion correction for PET data using subspace-based real-time MR imaging in simultaneous PET/MR
Marin T, Djebra Y, Han P, Chemli Y, Bloch I, Fakhri G, Ouyang J, Petibon Y, Ma C. Motion correction for PET data using subspace-based real-time MR imaging in simultaneous PET/MR. Physics In Medicine And Biology 2020, 65: 235022. PMID: 33263317, PMCID: PMC7985095, DOI: 10.1088/1361-6560/abb31d.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementMultimodal ImagingPositron-Emission TomographyTime FactorsConceptsPositron emission tomography reconstructionMotion-corrected PET reconstructionsPET reconstructionMotion-corrected PET imagesIrregular respiratory motionMotion fieldMotion correction methodMotion correction approachIrregular motion patternsUndersampled k-space dataImage quality of positron emission tomographyQuality of positron emission tomographyMotion patternsLow-rank characteristicsRespiratory motionContrast-to-noise ratioEstimated motion fieldSurrogate signalsMotion correctionK-space dataImage qualityReal-time MR imagingSimultaneous PET/MRMotion artifact reductionPET/MR scannersMR‐based PET attenuation correction using a combined ultrashort echo time/multi‐echo Dixon acquisition
Han P, Horng D, Gong K, Petibon Y, Kim K, Li Q, Johnson K, Fakhri G, Ouyang J, Ma C. MR‐based PET attenuation correction using a combined ultrashort echo time/multi‐echo Dixon acquisition. Medical Physics 2020, 47: 3064-3077. PMID: 32279317, PMCID: PMC7375929, DOI: 10.1002/mp.14180.Peer-Reviewed Original ResearchMeSH KeywordsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission TomographyTomography, X-Ray ComputedConceptsLinear attenuation coefficientPositron emission tomography attenuation correctionPhysical compartmental modelAttenuation correctionShort T<sub>2</sub> componentPET attenuation correctionRadial k-space trajectoryMagnetic resonance (MR)-based methodK-space trajectoriesRadial trajectoryK-spaceAttenuation coefficientDixon acquisitionsPositron emission tomographyWhole white matterMuting methodImage reconstructionImaging speedMR signalMRAC methodPositron emission tomography imagingCorrectionGray matter regionsPhantomMatter regions
2019
MR-based cardiac and respiratory motion correction of PET: application to static and dynamic cardiac 18F-FDG imaging
Petibon Y, Sun T, Han P, Ma C, Fakhri G, Ouyang J. MR-based cardiac and respiratory motion correction of PET: application to static and dynamic cardiac 18F-FDG imaging. Physics In Medicine And Biology 2019, 64: 195009. PMID: 31394518, PMCID: PMC7007962, DOI: 10.1088/1361-6560/ab39c2.Peer-Reviewed Original ResearchConceptsMR-based motion correctionRespiratory motion correctionMotion correctionImproved spatial resolutionReconstructed activity concentrationCardiac PET dataSpatial resolutionCoincidence eventsMR-basedPET imagingContrast-to-noise ratioCardiac PET imagingRespiratory phasesMC dataImprove image qualityMR acquisitionQuantitative accuracyCardiac PETPET dataActivity concentrationsMyocardium wallF-FDG PETDynamics studiesImage qualityMotion artifactsFree-Breathing Three-Dimensional T1 Mapping of the Heart Using Subspace-Based Data Acquisition and Image Reconstruction
Han P, Horng D, Marin T, Petibon Y, Ouyang J, Fakhri G, Ma C. Free-Breathing Three-Dimensional T1 Mapping of the Heart Using Subspace-Based Data Acquisition and Image Reconstruction. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2019, 00: 4008-4011. PMID: 31946750, DOI: 10.1109/embc.2019.8856511.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHeartImage EnhancementImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMyocardiumRespirationConceptsRespiratory motionRespiratory gatingLongitudinal relaxation timeSubspace-based methodsLow-rank tensorMagnetic resonance imagingRelaxation timeT1 mappingT)-spaceSubspace-basedSparsity constraintDynamic MR imagingReconstructed mapsSpatiotemporal correlationThree-dimensionalCardiac MRHealthy subjectsIn vivo dataMagnetizationResonance imagingImage functionMR imagingData acquisitionClinical applicationTensor
2016
Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR
Petibon Y, Guehl N, Reese T, Ebrahimi B, Normandin M, Shoup T, Alpert N, Fakhri G, Ouyang J. Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR. Physics In Medicine And Biology 2016, 62: 326-343. PMID: 27997375, PMCID: PMC5241952, DOI: 10.1088/1361-6560/aa5087.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementMyocardial Perfusion ImagingMyocardiumPositron-Emission TomographySwineConceptsSimultaneous PET-MRPET myocardial perfusion imagingMyocardial perfusion imagingPoint spread functionPoint-spread function correctionUngated dataMotion correctionPET-MRPartial volume effectsApparent wall thicknessMyocardial blood flowPartial volume effect correctionMR-based motion correctionMotion fieldPET-MR scannersPoint spread function modelPET dataPerfusion imagingImage qualityImpact of motionDynamic myocardial perfusion imagingAttenuation mapNon-rigid registrationAbsolute myocardial blood flowUngated images
2015
Continuous MR bone density measurement using water- and fat-suppressed projection imaging (WASPI) for PET attenuation correction in PET-MR
Huang C, Ouyang J, Reese T, Wu Y, Fakhri G, Ackerman J. Continuous MR bone density measurement using water- and fat-suppressed projection imaging (WASPI) for PET attenuation correction in PET-MR. Physics In Medicine And Biology 2015, 60: n369-n381. PMID: 26405761, PMCID: PMC4607313, DOI: 10.1088/0031-9155/60/20/n369.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueBone and BonesBone DensityHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission TomographyWaterConceptsAttenuation correctionUltrashort echo timeMR-based attenuation correctionProjection imagesPET attenuation correctionMR attenuation correctionPET-MRPulse sequenceEcho timeDensity variationsPET imagingCorrectionBone density variationWASPIDensity measurementsAttenuation variationsPhantomMR sequencesLack of signalPulseAttenuationAccelerated acquisition of tagged MRI for cardiac motion correction in simultaneous PET‐MR: Phantom and patient studies
Huang C, Petibon Y, Ouyang J, Reese T, Ahlman M, Bluemke D, El Fakhri G. Accelerated acquisition of tagged MRI for cardiac motion correction in simultaneous PET‐MR: Phantom and patient studies. Medical Physics 2015, 42: 1087-1097. PMID: 25652521, PMCID: PMC4312342, DOI: 10.1118/1.4906247.Peer-Reviewed Original ResearchMeSH KeywordsHeartHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementPhantoms, ImagingPositron-Emission TomographyTime FactorsConceptsPET motion correctionMotion correctionSimultaneous PET-MRTMR dataPET list-mode dataPET-MRList-mode dataCardiac motion correctionPET-MR scannersImage qualityParallel imagingAcquisition timePET imagingRespiratory motionCompressive sensingMotion fieldAttenuation correctionDefect contrastModerate acceleration factorsDegradation of image qualityTagged MRCardiac phantomLong acquisition timesPhantomAccurate motion field
2014
Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging
Petibon Y, Huang C, Ouyang J, Reese T, Li Q, Syrkina A, Chen Y, Fakhri G. Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging. Medical Physics 2014, 41: 042503. PMID: 24694156, PMCID: PMC3971824, DOI: 10.1118/1.4868458.Peer-Reviewed Original ResearchConceptsPoint spread function modelRespiratory motionPoint spread functionPET-MR scannersPencil-beam navigator echoesPET-MRMeasurement of respiratory motionPSF modelRespiratory motion correctionDetector blur effectsModel respiratory motionLung-liver interfacePatient studiesLesion contrastSimultaneous PET-MRSource of image degradationWhole-body PET imagingPET reconstruction algorithmMoving lesionsPhantom experiment resultsPET eventsContrast recoveryNavigator echoesIterative reconstruction processMotion correctionMR‐based motion correction for PET imaging using wired active MR microcoils in simultaneous PET‐MR: Phantom study
Huang C, Ackerman J, Petibon Y, Brady T, Fakhri G, Ouyang J. MR‐based motion correction for PET imaging using wired active MR microcoils in simultaneous PET‐MR: Phantom study. Medical Physics 2014, 41: 041910. PMID: 24694141, PMCID: PMC3978416, DOI: 10.1118/1.4868457.Peer-Reviewed Original ResearchMeSH KeywordsArtifactsBrainImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementPhantoms, ImagingPositron-Emission TomographyTime FactorsConceptsMotion correctionMR-based motion correctionStatic phantom dataPET quantitative accuracyPET-MRPET-MR scannersSimultaneous PET-MRHoffman phantomList-modePositron emission tomography imagingPET reconstructionBrain positron emission tomographyIterative PET reconstructionPhantom dataPhantomQuantitative accuracyIndependent noise realizationsImage contrastNoise realizationsHead motionPET dataPositron emission tomographyStatic referenceBrain PET scansMotion artifactsMotion compensation for brain PET imaging using wireless MR active markers in simultaneous PET–MR: Phantom and non-human primate studies
Huang C, Ackerman J, Petibon Y, Normandin M, Brady T, Fakhri G, Ouyang J. Motion compensation for brain PET imaging using wireless MR active markers in simultaneous PET–MR: Phantom and non-human primate studies. NeuroImage 2014, 91: 129-137. PMID: 24418501, PMCID: PMC3965607, DOI: 10.1016/j.neuroimage.2013.12.061.Peer-Reviewed Original ResearchConceptsMotion correctionWireless markersList-mode reconstructionReconstructed PET imagesMotion correction techniqueObserver signal-to-noise ratioSimultaneous PET-MRMotion artifactsPET phantomPET contrastPET reconstructionBrain PET imagingPET imagingPhantomBrain PETPET-MRIndependent noise realizationsAccurate quantitative valuesHead motionNoise realizationsPET dataSignal-to-noise ratioStatic referenceBrain PET scansActivation markers
2013
Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study
Petibon Y, Ouyang J, Zhu X, Huang C, Reese T, Chun S, Li Q, Fakhri G. Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study. Physics In Medicine And Biology 2013, 58: 2085-2102. PMID: 23470288, PMCID: PMC3657754, DOI: 10.1088/0031-9155/58/7/2085.Peer-Reviewed Original ResearchMeSH KeywordsHeartHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementMyocardiumPhantoms, ImagingPositron-Emission TomographyRadiation DosageTime FactorsConceptsContrast recoveryDetector point spread functionPartial volume effectsK-spaceMotion compensationB-spline registrationLesion-detection studiesCardiac motion compensationPET-MR scannersSimultaneous PET-MRPET contrastIterative reconstruction frameworkPoint spread functionMotion correctionPET countsNon-rigid B-spline registrationCardiac phantomPSF modelPET-MRMotion deblurringReconstruction frameworkSystem matrixCardiac PETSpread functionDefect detectionMagnetic Resonance-Based Motion Correction for Positron Emission Tomography Imaging
Ouyang J, Li Q, Fakhri G. Magnetic Resonance-Based Motion Correction for Positron Emission Tomography Imaging. Seminars In Nuclear Medicine 2013, 43: 60-67. PMID: 23178089, PMCID: PMC3508789, DOI: 10.1053/j.semnuclmed.2012.08.007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMovementPhantoms, ImagingPositron-Emission TomographyConceptsMotion correctionClinical whole-body PET scannersMotion-corrected PET imagesWhole-body PET scannerPET motion correctionNonrigid image registration algorithmAcquired MR imagesRespiratory motionImage registration algorithmPET scannerSimultaneous PET/magnetic resonancePET reconstructionSimultaneous PET/MRPatient motionImage qualityIterative PET reconstructionPET/MR studiesPET/magnetic resonanceAttenuating mediaImage artifactsRegistration algorithmSpatial resolutionReconstruction algorithmPositron emission tomographyMR imaging techniques
2012
MRI-Based Nonrigid Motion Correction in Simultaneous PET/MRI
Chun Y, Reese T, Ouyang J, Guerin B, Catana C, Zhu X, Alpert N, Fakhri G. MRI-Based Nonrigid Motion Correction in Simultaneous PET/MRI. Journal Of Nuclear Medicine 2012, 53: 1284-1291. PMID: 22743250, PMCID: PMC4077320, DOI: 10.2967/jnumed.111.092353.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArtifactsMacaca mulattaMagnetic Resonance ImagingMaleMovementPhantoms, ImagingPositron-Emission TomographyRabbitsRespirationTime FactorsConceptsChannelized Hotelling observerMotion correctionDetection signal-to-noise ratioSignal-to-noise ratioMRI-based motion correctionRespiratory motion correctionMotion-corrected reconstructionOrdered-subsets expectation maximization algorithmNonrigid motion correctionChannelized Hotelling observer studyPET image qualityNonrigid image registration methodCoincidence dataDeformable phantomRespiratory gatingReduce radiation doseDynamic phantomImage registration methodReduced signal-to-noise ratioSimultaneous PET/MRICost of increased noiseHotelling observerPhantomAttenuation measurementsRabbit studies