2017
Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies
Petibon Y, Rakvongthai Y, Fakhri G, Ouyang J. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies. Physics In Medicine And Biology 2017, 62: 3539-3565. PMID: 28379843, PMCID: PMC5739089, DOI: 10.1088/1361-6560/aa6394.Peer-Reviewed Original ResearchConceptsPET sinogramsSignal-to-noise ratioList-mode PET dataSiemens Biograph mMR scannerList-mode dataMyocardial perfusion imagingNoise realizationsPET myocardial perfusion imagingLow count levelsLeast-squares fitBiograph mMR scannerPET projection dataOriginal list-mode dataMyocardial blood flowCount levelsParametric reconstructionOSEMReconstruction methodIndependent noise realizationsNormal count levelsSinogramDirect reconstructionDynamic sinogramsKinetic modelPoor signal-to-noise ratio
2014
Myocardial Defect Detection Using PET-CT: Phantom Studies
Mananga E, Fakhri G, Schaefferkoetter J, Bonab A, Ouyang J. Myocardial Defect Detection Using PET-CT: Phantom Studies. PLOS ONE 2014, 9: e88200. PMID: 24505429, PMCID: PMC3914931, DOI: 10.1371/journal.pone.0088200.Peer-Reviewed Original ResearchConceptsMyocardial defect detectionFiltered back projectionChannelized Hotelling observerPhantom studyActivity distributionSubset expectation maximizationDefect detectionCardiac PET studiesMyocardial defectsHotelling observerNoise levelBack-projectionPET-CTPhantomExpectation maximizationOP-OSEMReconstruction schemePET studiesOSEMDefectsNoise
2013
Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies
Rakvongthai Y, Fakhri G, Lim R, Bonab A, Ouyang J. Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies. Medical Physics 2013, 40: 102506. PMID: 24089927, PMCID: PMC3785531, DOI: 10.1118/1.4820977.Peer-Reviewed Original ResearchConceptsScatter correctionDual-radionuclideContrast recoveryPhantom studyAnthropomorphic torso phantomPatient studiesTumor uptakeTumor imagingSPECT projectionsTorso phantomMonte-CarloPhantom dataPhantomIterative reconstructionOSEMProjection dataDR dataIncrease patient throughputNoise realizationsSPECT-CTImage reconstructionClinical studiesTumorTumor projectionPoisson noise
2009
Quantitative simultaneous cardiac SPECT using MC‐JOSEM
Ouyang J, Zhu X, Trott C, Fakhri G. Quantitative simultaneous cardiac SPECT using MC‐JOSEM. Medical Physics 2009, 36: 602-611. PMID: 19292000, PMCID: PMC2673670, DOI: 10.1118/1.3063544.Peer-Reviewed Original ResearchConceptsMC-JOSEMEnergy windowWater-filled torso phantomScatter correctionPhotopeak energy windowStandard OSEMCardiac SPECT imagingActivity concentration ratioIterative reconstruction algorithmReconstruction algorithmMyocardium wallTorso phantomActivity estimationDetector responseEmission energyBackground compartmentPhantom dataCardiac SPECTActivity distributionRest/stress imagingScatteringCases of patientsOSEMChest painCardiac protocols