2017
Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies
Petibon Y, Rakvongthai Y, Fakhri G, Ouyang J. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies. Physics In Medicine And Biology 2017, 62: 3539-3565. PMID: 28379843, PMCID: PMC5739089, DOI: 10.1088/1361-6560/aa6394.Peer-Reviewed Original ResearchConceptsPET sinogramsSignal-to-noise ratioList-mode PET dataSiemens Biograph mMR scannerList-mode dataMyocardial perfusion imagingNoise realizationsPET myocardial perfusion imagingLow count levelsLeast-squares fitBiograph mMR scannerPET projection dataOriginal list-mode dataMyocardial blood flowCount levelsParametric reconstructionOSEMReconstruction methodIndependent noise realizationsNormal count levelsSinogramDirect reconstructionDynamic sinogramsKinetic modelPoor signal-to-noise ratio
2016
A Bayesian spatial temporal mixtures approach to kinetic parametric images in dynamic positron emission tomography
Zhu W, Ouyang J, Rakvongthai Y, Guehl N, Wooten D, Fakhri G, Normandin M, Fan Y. A Bayesian spatial temporal mixtures approach to kinetic parametric images in dynamic positron emission tomography. Medical Physics 2016, 43: 1222-1234. PMID: 26936707, PMCID: PMC5025019, DOI: 10.1118/1.4941010.Peer-Reviewed Original ResearchConceptsPositron emission tomographySpatial mixture modelNearby voxelsMixture modelEmission tomographyDynamic positron emission tomographyK-means methodKinetic modelKinetic parametric imagesOne-compartment kinetic modelNovel algorithmTemporal informationClassification purposesMeasurement of local perfusionLocal perfusionTime activity curvesNormal ROIsTemporal modelBayesian algorithmCardiac studiesMarkov chain Monte CarloParameter estimationNoise regionSimulation experimentsSimulated data sets