2017
Structural insights into the oligomerization of FtsH periplasmic domain from Thermotoga maritima
An JY, Sharif H, Kang GB, Park KJ, Lee JG, Lee S, Jin MS, Song JJ, Wang J, Eom SH. Structural insights into the oligomerization of FtsH periplasmic domain from Thermotoga maritima. Biochemical And Biophysical Research Communications 2017, 495: 1201-1207. PMID: 29180014, DOI: 10.1016/j.bbrc.2017.11.158.Peer-Reviewed Original ResearchConceptsPeriplasmic domainMisfolded membrane proteinsATP-dependent proteaseMembrane protein complexesResolution crystal structureHydrophobic membrane environmentMembrane homeostasisProtein complexesMembrane proteinsTransmembrane proteinMembrane environmentThermotoga maritimaStructural insightsFtsHProtease domainToxic proteinsProteinOligomerizationHigh energetic barrierDomainTranslocatesEnergetic barrierMaritimaHomeostasisCrystal structureSystematic analysis of residual density suggests that a major limitation in well‐refined X‐ray structures of proteins is the omission of ordered solvent
Wang J. Systematic analysis of residual density suggests that a major limitation in well‐refined X‐ray structures of proteins is the omission of ordered solvent. Protein Science 2017, 26: 1012-1023. PMID: 28244185, PMCID: PMC5405434, DOI: 10.1002/pro.3145.Peer-Reviewed Original Research
2016
Destruction‐and‐diffraction by X‐ray free‐electron laser
Wang J. Destruction‐and‐diffraction by X‐ray free‐electron laser. Protein Science 2016, 25: 1585-1592. PMID: 27262052, PMCID: PMC5338243, DOI: 10.1002/pro.2959.Peer-Reviewed Original ResearchConceptsX-ray free-electron lasersFree-electron laserSingle femtosecond pulseAtomic scattering factorsFemtosecond pulsesRecent theoretical studiesScattering factorsSuch pulsesElectronic processesDifferent atomsCrystallographic data collectionRadiation damageSingle pulseX-rayPulsesLaserSuch crystalsTheoretical studyCrystalsDiffractionMacromolecular crystalsFemtosecondExperimental evidenceAtomsRadiation