1996
Structure of Taq polymerase with DNA at the polymerase active site
Eom S, Wang J, Steitz T. Structure of Taq polymerase with DNA at the polymerase active site. Nature 1996, 382: 278-281. PMID: 8717047, DOI: 10.1038/382278a0.Peer-Reviewed Original ResearchConceptsDuplex DNADNA polymeraseEnded duplex DNAKlenow fragmentBlunt-end terminiActive-site cleftEscherichia coli DNA polymerase IProtein side chainsDNA polymerase ICo-crystal structurePolymerase active siteTaq polymeraseWide minor groovePol ICommon binding sitePolymerase IPolymerase domainExonuclease domainPolymerase cleftThermus aquaticusPolymeraseDNAPolymerase siteMinor grooveExonuclease site
1995
Crystal structure of Thermus aquaticus DNA polymerase
Kim Y, Eom S, Wang J, Lee D, Suh S, Steitz T. Crystal structure of Thermus aquaticus DNA polymerase. Nature 1995, 376: 612-616. PMID: 7637814, DOI: 10.1038/376612a0.Peer-Reviewed Original Research