Crystal Structure of d-Hydantoinase from Bacillus stearothermophilus: Insight into the Stereochemistry of Enantioselectivity † , ‡
Cheon YH, Kim HS, Han KH, Abendroth J, Niefind K, Schomburg D, Wang J, Kim Y. Crystal Structure of d-Hydantoinase from Bacillus stearothermophilus: Insight into the Stereochemistry of Enantioselectivity † , ‡. Biochemistry 2002, 41: 9410-9417. PMID: 12135362, DOI: 10.1021/bi0201567.Peer-Reviewed Original ResearchConceptsD-hydantoinaseExocyclic substituentsTIM-barrel foldStriking structural similarityApo crystal structureSubstrate recognitionBarrel foldCatalytic chemistryStructural comparisonSide-chain precursorBacillus stearothermophilusCrystal structureAmino acidsStructural similarityDihydroorotaseHydantoinsStereochemistrySubstituentsEnantioselectivityEnzymeStereospecific hydrolysisHydrolysisStructureChemistryHydantoinase