1992
Transcriptional regulation of the human IgE receptor (Fc epsilon RII/CD23) by EBV. Identification of EBV-responsive regulatory elements in intron 1.
Lacy J, Rudnick H. Transcriptional regulation of the human IgE receptor (Fc epsilon RII/CD23) by EBV. Identification of EBV-responsive regulatory elements in intron 1. The Journal Of Immunology 1992, 148: 1554-60. PMID: 1311350, DOI: 10.4049/jimmunol.148.5.1554.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, Differentiation, B-LymphocyteAntigens, ViralBase SequenceChloramphenicol O-AcetyltransferaseEnhancer Elements, GeneticEpstein-Barr Virus Nuclear AntigensHerpesvirus 4, HumanHumansImmunoglobulin EIntronsMolecular Sequence DataReceptors, FcReceptors, IgERNA, MessengerTranscription, GeneticConceptsRegulatory elementsTranscriptional activationSpecific DNA-protein complexesIntron 1DNA-protein complexesMaintenance of immortalizationTranscriptional regulatory elementsMobility shift assaysReporter gene assayNuclear runoff analysisAdjacent flanking regionsTranscriptional regulationLymphoma linesIntron sequencesNuclear proteinsShift assaysFirst intronEnhancer activityHeterologous promoterReporter geneFlanking regionsEnhancer elementsMolecular mechanismsGene assayGenes
1990
Macrophage colony-stimulating factor production by murine and human keratinocytes. Enhancement by bacterial lipopolysaccharide.
Chodakewitz J, Lacy J, Edwards S, Birchall N, Coleman D. Macrophage colony-stimulating factor production by murine and human keratinocytes. Enhancement by bacterial lipopolysaccharide. The Journal Of Immunology 1990, 144: 2190-6. PMID: 2179407, DOI: 10.4049/jimmunol.144.6.2190.Peer-Reviewed Original Research
1989
Post-transcriptional mechanisms of deregulation of MYC following conversion of a human B cell line by Epstein-Barr virus.
Lacy J, Summers W, Summers W. Post-transcriptional mechanisms of deregulation of MYC following conversion of a human B cell line by Epstein-Barr virus. The EMBO Journal 1989, 8: 1973-80. PMID: 2551670, PMCID: PMC401064, DOI: 10.1002/j.1460-2075.1989.tb03603.x.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusB cell linesBJAB cellsNegative Burkitt lymphoma linesPresence of EBVLymphoma linesBurkitt lymphoma linesCell linesNormal human B cellsHuman B cell linesHuman B cellsMYC mRNAEBV genomeVitro infectionMyc transcriptsB cellsEBVLymphoblastoid linesMYC expressionVirusMechanism of deregulationCellsPost-transcriptional mechanismsMYC