Evolution of peroxisome proliferator-activated receptor gamma alternative splicing.
Dou T, Xu J, Gao Y, Gu J, Ji C, Xie Y, Zhou Y. Evolution of peroxisome proliferator-activated receptor gamma alternative splicing. Frontiers In Bioscience-Elite 2010, 2: 1334-43. PMID: 20515805, DOI: 10.2741/e193.Peer-Reviewed Original ResearchConceptsKa/KsGamma geneHigher Ka/KsAlternative splicing exonsDifferent transcript variantsPPAR-gamma geneAdaptive evolutionVertebrate speciesAlternative splicingEvolutionary changeAlternative exonsEST dataGenomic sequencesNew exonsPeroxisome proliferator-activated receptor gammaTranscript variantsProliferator-activated receptor gammaConstitutive counterpartExonsGenesReceptor gammaGlucose homeostasisVertebratesImportant roleSplicing