Assessment of tumor mutation burden calculation from gene panel sequencing data
Xu Z, Dai J, Wang D, Lu H, Dai H, Ye H, Gu J, Chen S, Huang B. Assessment of tumor mutation burden calculation from gene panel sequencing data. OncoTargets And Therapy 2019, 12: 3401-3409. PMID: 31123404, PMCID: PMC6510391, DOI: 10.2147/ott.s196638.Peer-Reviewed Original ResearchTumor mutation burdenNon-small cell lung cancerHigh tumor mutation burdenImmune checkpoint blockadeCell lung cancerCancer Genome AtlasCheckpoint blockadeLung cancerClinical trialsSelection biomarkerMutation burdenCancer typesWhole-exome sequencing dataGenome AtlasPanel sequencing dataTargeted sequencingClinical applicationExome sequencing dataBurden calculationsWhole-genome sequencingMutation levelsSomatic mutation data