Early Gonadal Development: Exploring Wt1 and Sox9 Function
Guo J, Hammes A, Chaboissier M, Vidal V, Xing Y, Wong F, Schedl A. Early Gonadal Development: Exploring Wt1 and Sox9 Function. Novartis Foundation Symposia 2002, 244: 23-34. PMID: 11990794, DOI: 10.1002/0470868732.ch3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFemaleHigh Mobility Group ProteinsMaleOvarySex Determination ProcessesSex DifferentiationSOX9 Transcription FactorTestisTranscription FactorsWT1 ProteinsConceptsSox9 functionSex determinationSex-determining gene SRYSex-determining signalWilms' tumor suppressorFemale sex reversalBipotential primordiumGonad formationGene SRYXX gonadsTransgenic experimentsFirst geneGonadal primordiumMouse developmentPosttranscriptional modificationsKnockout experimentsSex reversalHuman SOX9Distinct functionsSRY geneGonadal anlageSOX9 geneTumor suppressorImportant regulatorGenes