Erythropoietin expands a stromal cell population that can mediate renoprotection
Bi B, Guo J, Marlier A, Lin SR, Cantley LG. Erythropoietin expands a stromal cell population that can mediate renoprotection. American Journal Of Physiology. Renal Physiology 2008, 295: f1017-f1022. PMID: 18653480, PMCID: PMC2576137, DOI: 10.1152/ajprenal.90218.2008.Peer-Reviewed Original ResearchConceptsAdministration of EPOMarrow stromal cellsTubular epithelial cellsRenoprotective effectsTubular cellsCisplatin-treated miceEpithelial cellsEndothelial progenitor cellsSecretion of factorsStromal cell populationsDeprivation-induced cell deathRenal functionTubular injuryCisplatin administrationPeripheral circulationIntraperitoneal injectionSerum deprivation-induced cell deathToxic injuryBone marrowStromal cellsVivo expansionInjuryProgenitor cellsAdministrationEPO receptor