2008
Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia
Braithwaite SP, Xu J, Leung J, Urfer R, Nikolich K, Oksenberg D, Lombroso PJ, Shamloo M. Expression and function of striatal enriched protein tyrosine phosphatase is profoundly altered in cerebral ischemia. European Journal Of Neuroscience 2008, 27: 2444-2452. PMID: 18445231, PMCID: PMC2738830, DOI: 10.1111/j.1460-9568.2008.06209.x.Peer-Reviewed Original ResearchConceptsStriatal enriched protein tyrosine phosphataseProtein tyrosine phosphataseTyrosine phosphatasePost-transcriptional levelNovel speciesPhosphorylation stateImportant proteinsMature formKey substrateNMDA receptor subunitsReceptor subunitsActive formSynaptic functionComplex cascadeCritical roleERKMRNA levelsProteinMRNAPERKPhosphataseCleavageCentral nervous systemNervous systemSubunits
2002
Cloning, expression and characterization of a novel human VMP gene*
Cheng C, Xu J, Ye X, Dai J, Wu Q, Zeng L, Wang L, Zhao W, Ji C, Gu S, Xie Y, Mao Y. Cloning, expression and characterization of a novel human VMP gene*. Molecular Biology Reports 2002, 29: 281-286. PMID: 12463420, DOI: 10.1023/a:1020402410522.Peer-Reviewed Original ResearchConceptsMembrane proteinsVesicular membrane proteinsNovel human genePutative molecular weightNeuron-specific membrane proteinMicrotubule-binding domainPutative membraneRT-PCR analysisHuman genesOrganelle transportVmp genesC-terminalAmino acidsCloningGenesProteinHydrophilic tailImportant roleCDNAMolecular weightMicrotubulesDomainKDaExpression
2001
Cloning, expression and characterization of a novel human REPS1 gene1The nucleotide sequence reported in this paper has been submitted to GenBank under accession number AF251052.1
Xu J, Zhou Z, Zeng L, Huang Y, Zhao W, Cheng C, Xu M, Xie Y, Mao Y. Cloning, expression and characterization of a novel human REPS1 gene1The nucleotide sequence reported in this paper has been submitted to GenBank under accession number AF251052.1. Biochimica Et Biophysica Acta 2001, 1522: 118-121. PMID: 11750063, DOI: 10.1016/s0167-4781(01)00310-4.Peer-Reviewed Original ResearchConceptsHuman fetal brain libraryFetal brain libraryAmino acid identitySignal transduction pathwaysDownstream target proteinsNorthern blot analysisProtein familySmall GTPaseBinding partnerAcid identityTransduction pathwaysNucleotide sequenceVariety of tissuesBrain libraryTarget proteinsReps1Blot analysisProteinRalBP1Recent findingsStrong expressionExpressionRalGTPaseImportant role