2024
Sex Modifies the Severity and Outcome of Spontaneous Intracerebral Hemorrhage
Rivier C, Renedo D, Marini S, Magid‐Bernstein J, de Havenon A, Rosand J, Hanley D, Ziai W, Mayer S, Woo D, Sansing L, Sheth K, Anderson C, Falcone G. Sex Modifies the Severity and Outcome of Spontaneous Intracerebral Hemorrhage. Annals Of Neurology 2024 PMID: 39499118, DOI: 10.1002/ana.27123.Peer-Reviewed Original ResearchRisk of hematoma expansionHighest risk of hematoma expansionRisk of poor outcomesIntracerebral hemorrhageHematoma expansionHigh riskMale sexPoor outcomeOutcome of spontaneous intracerebral hemorrhageClinical characteristics of patientsStudies of intracerebral hemorrhageNon-traumatic intracerebral hemorrhageIndividual patient data meta-analysisPatient data meta-analysisSpontaneous intracerebral hemorrhageSingle-center studyIntracerebral hemorrhage patientsHigh risk of expansionCharacteristics of patientsIntracerebral hemorrhage severityPoor functional outcomeRandomized clinical trialsData meta-analysisHemorrhage volumeClinical characteristics
2020
Red Blood Cell Transfusions and Outcomes After Intracerebral Hemorrhage
Roh DJ, Carvalho Poyraz F, Magid-Bernstein J, Elkind MSV, Agarwal S, Park S, Claassen J, Connolly ES, Hod E, Murthy SB. Red Blood Cell Transfusions and Outcomes After Intracerebral Hemorrhage. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 105317. PMID: 32992186, PMCID: PMC7686150, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105317.Peer-Reviewed Original ResearchConceptsRBC transfusionICH outcomeDisease severityComorbidity burdenICH hospitalizationsPoor outcomeRed blood cell transfusionICD-9-CM codesBlood cell transfusionAdditional prospective studiesRed blood cell levelsIntracerebral hemorrhage outcomesNationwide Inpatient SampleLower red blood cell levelsBlood cell levelsBaseline comorbiditiesHospital mortalityTransfusion exposureVentriculostomy drainsCell transfusionLow comorbidityIntracerebral hemorrhageMechanical ventilationProspective studyInpatient Sample
2019
Low hemoglobin and hematoma expansion after intracerebral hemorrhage.
Roh DJ, Albers DJ, Magid-Bernstein J, Doyle K, Hod E, Eisenberger A, Murthy S, Witsch J, Park S, Agarwal S, Connolly ES, Elkind MSV, Claassen J. Low hemoglobin and hematoma expansion after intracerebral hemorrhage. Neurology 2019, 93: e372-e380. PMID: 31209179, PMCID: PMC6669932, DOI: 10.1212/wnl.0000000000007820.Peer-Reviewed Original ResearchConceptsAdmission hemoglobin levelsLower admission hemoglobin levelsLower hemoglobin levelsHemoglobin levelsHematoma expansionLower hemoglobinWorse outcomesMultivariable logistic regression modelSeparate multivariable logistic regression modelsPoor clinical outcomeMeeting inclusion criteriaIntracerebral hemorrhage volumeLogistic regression modelsAdmission hemoglobinRankin ScaleCohort studyConsecutive patientsClinical outcomesIntracerebral hemorrhagePoor outcomeICH outcomeICH scoreHemorrhage volumeModifiable targetsInclusion criteriaAdmission Hemoglobin Level is Associated with Hematoma Expansion and Poor Outcome after Intracerebral Hemorrhage (S2.001)
Magid-Bernstein J, Albers D, Doyle K, Hod E, Eisenberger A, Murthy S, Park S, Agarwal S, Connolly E, Elkind M, Claassen J, Roh D. Admission Hemoglobin Level is Associated with Hematoma Expansion and Poor Outcome after Intracerebral Hemorrhage (S2.001). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.s2.001.Peer-Reviewed Original Research
2017
Prognostic Value of the Neurological Examination in Cardiac Arrest Patients After Therapeutic Hypothermia
Matthews EA, Magid-Bernstein J, Sobczak E, Velazquez A, Falo CM, Park S, Claassen J, Agarwal S. Prognostic Value of the Neurological Examination in Cardiac Arrest Patients After Therapeutic Hypothermia. The Neurohospitalist 2017, 8: 66-73. PMID: 29623156, PMCID: PMC5882011, DOI: 10.1177/1941874417733217.Peer-Reviewed Original ResearchPositive predictive valuePupillary light responseTherapeutic hypothermiaNeurological examinationCorneal reflexPredictive valueDay 3Poor outcomePrognostic valueDay 5Cerebral Performance Category scoreUniversity intensive care unitTime pointsCardiac arrest patientsCardiac arrest survivorsIntensive care unitLife-sustaining therapyNegative predictive valueLeast day 5False positive rateHospital dischargeArrest patientsArrest survivorsCare unitIdeal timingCategorization of survival and death after cardiac arrest
Matthews EA, Magid-Bernstein J, Presciutti A, Rodriguez A, Roh D, Park S, Claassen J, Agarwal S. Categorization of survival and death after cardiac arrest. Resuscitation 2017, 114: 79-82. PMID: 28279695, PMCID: PMC5548414, DOI: 10.1016/j.resuscitation.2017.03.005.Peer-Reviewed Original ResearchConceptsCerebral Performance CategoryPoor neurological prognosisNeurological prognosisFamily's wishesPoor outcomeMost cardiac arrest patientsFavorable recoveryOne-yearEarly recovery groupUnfavorable neurological prognosisCardiac arrest patientsLife-sustaining therapyHemodynamic instabilityFavorable prognosisArrest patientsCardiac arrestGOC discussionsWorse outcomesPatient outcomesBrain deathCommon causeEarly recoveryCare conversationsRecovery groupMost survivors