2024
Risk of Severe Hypoglycemia After Initiation of Noninsulin Glucose-Lowering Therapies in Adults With Type 2 Diabetes at Moderate Cardiovascular Disease Risk
McCoy R, Swarna K, Neumiller J, Polley E, Deng Y, Mickelson M, Herrin J. Risk of Severe Hypoglycemia After Initiation of Noninsulin Glucose-Lowering Therapies in Adults With Type 2 Diabetes at Moderate Cardiovascular Disease Risk. Clinical Diabetes 2024 DOI: 10.2337/cd24-0007.Peer-Reviewed Original ResearchSodium-glucose cotransporter 2Moderate cardiovascular disease riskRisk of severe hypoglycemiaGlucose-lowering therapyCardiovascular disease riskType 2 diabetesSevere hypoglycemiaSodium-glucose cotransporter 2 inhibitorsDPP-4GLP-1 receptor agonistsGlucagon-like peptide 1Risk of hypoglycemiaDPP-4 inhibitorsDipeptidyl peptidase 4Disease riskAvoidance of hypoglycemiaSulfonylurea therapyReceptor agonistsCotransporter 2Sulfonylurea usePatient populationGLP-1Peptidase 4HypoglycemiaEmergency department
2018
Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma
Hess EP, Homme JL, Kharbanda AB, Tzimenatos L, Louie JP, Cohen DM, Nigrovic LE, Westphal JJ, Shah ND, Inselman J, Ferrara MJ, Herrin J, Montori VM, Kuppermann N. Effect of the Head Computed Tomography Choice Decision Aid in Parents of Children With Minor Head Trauma. JAMA Network Open 2018, 1: e182430. PMID: 30646167, PMCID: PMC6324506, DOI: 10.1001/jamanetworkopen.2018.2430.Peer-Reviewed Original ResearchConceptsMinor head traumaIntermediate riskHead traumaParents of childrenComputed tomographyDecisional conflictUsual careEmergency departmentImportant traumatic brain injuryCT ratesDecision aid armPatients' mean ageUsual care armUS emergency departmentsHealth care utilizationAvailable diagnostic optionsTraumatic brain injuryDecision aidChildren ages 2Care armSecondary outcomesPrimary outcomeCare utilizationNonwhite raceEligible participants
2014
Effectiveness of the head CT choice decision aid in parents of children with minor head trauma: study protocol for a multicenter randomized trial
Hess EP, Wyatt KD, Kharbanda AB, Louie JP, Dayan PS, Tzimenatos L, Wootton-Gorges SL, Homme JL, RN L, LeBlanc A, Westphal JJ, Shepel K, Shah ND, Branda M, Herrin J, Montori VM, Kuppermann N. Effectiveness of the head CT choice decision aid in parents of children with minor head trauma: study protocol for a multicenter randomized trial. Trials 2014, 15: 253. PMID: 24965659, PMCID: PMC4081461, DOI: 10.1186/1745-6215-15-253.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryDiverse emergency departmentsMinor head traumaCranial CT scanHead traumaEmergency departmentCT scanUsual careHealthcare utilizationParents of childrenImportant traumatic brain injuryMethods/designThisProportion of patientsBlunt head traumaHospital billing recordsPatient-centered outcomesClinical prediction ruleAvailable diagnostic optionsHead CT scanDecision aidElectronic medical recordsClinician surveyMulticenter trialMedical recordsRisk factorsEffectiveness of the Chest Pain Choice decision aid in emergency department patients with low-risk chest pain: study protocol for a multicenter randomized trial
Anderson RT, Montori VM, Shah ND, Ting HH, Pencille LJ, Demers M, Kline JA, Diercks DB, Hollander JE, Torres CA, Schaffer JT, Herrin J, Branda M, Leblanc A, Hess EP. Effectiveness of the Chest Pain Choice decision aid in emergency department patients with low-risk chest pain: study protocol for a multicenter randomized trial. Trials 2014, 15: 166. PMID: 24884807, PMCID: PMC4031497, DOI: 10.1186/1745-6215-15-166.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAngina, UnstableCardiology Service, HospitalClinical ProtocolsCommunicationConflict, PsychologicalDecision Support TechniquesEmergency Service, HospitalHealth Knowledge, Attitudes, PracticeHealth ResourcesHumansMyocardial InfarctionPatient Education as TopicPhysician-Patient RelationsPredictive Value of TestsPrognosisResearch DesignRisk AssessmentRisk FactorsSurveys and QuestionnairesTime FactorsUnited StatesVideo RecordingConceptsAdvanced cardiac testingAcute coronary syndromeDiverse emergency departmentsEmergency departmentCardiac testingHealthcare utilizationLow-risk chest pain patientsLow-risk chest painMajor adverse cardiac eventsMethods/designThisAdverse cardiac eventsLow-risk patientsProportion of patientsChest pain patientsCommon reason patientsEmergency department patientsPatient-clinician discussionsHospital billing recordsPatient-centered outcomesElectronic medical recordsAvailable management optionsDecision aidChest painCoronary syndromeUsual care
2011
National Performance on Door-In to Door-Out Time Among Patients Transferred for Primary Percutaneous Coronary Intervention
Herrin J, Miller LE, Turkmani DF, Nsa W, Drye EE, Bernheim SM, Ling SM, Rapp MT, Han LF, Bratzler DW, Bradley EH, Nallamothu BK, Ting HH, Krumholz HM. National Performance on Door-In to Door-Out Time Among Patients Transferred for Primary Percutaneous Coronary Intervention. JAMA Internal Medicine 2011, 171: 1879-1886. PMID: 22123793, PMCID: PMC4312661, DOI: 10.1001/archinternmed.2011.481.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionDIDO timeCoronary interventionST-segment elevation acute myocardial infarctionMixed-effects multivariable modelElevation acute myocardial infarctionPrimary percutaneous coronary interventionMedian DIDO timeAcute myocardial infarctionFibrinolytic therapyPatient characteristicsMultivariable analysisEmergency departmentMyocardial infarctionHospital characteristicsMultivariable modelPatientsRural hospitalsHospitalMedicaid ServicesAge categoriesInterventionAfrican AmericansMinutesTreatment time
2010
Impact of Hospice Disenrollment on Health Care Use and Medicare Expenditures for Patients With Cancer
Carlson MD, Herrin J, Du Q, Epstein AJ, Barry CL, Morrison RS, Back AL, Bradley EH. Impact of Hospice Disenrollment on Health Care Use and Medicare Expenditures for Patients With Cancer. Journal Of Clinical Oncology 2010, 28: 4371-4375. PMID: 20805463, PMCID: PMC2954136, DOI: 10.1200/jco.2009.26.1818.Peer-Reviewed Original ResearchConceptsHealth care useHospice disenrollmentCare useMedicare expendituresHospice usersEmergency departmentIntensive care unit admissionEnd Results-Medicare dataHigher health care useDisease-directed treatmentCare unit admissionRate of hospitalizationIntensive care unitLargest diagnostic groupResult of cancerTotal Medicare expendituresHospital deathUnit admissionCare unitMultivariable analysisFamily caregiversPatientsHospice teamPatient careDiagnostic groups
2006
Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction
Bradley EH, Herrin J, Wang Y, Barton BA, Webster TR, Mattera JA, Roumanis SA, Curtis JP, Nallamothu BK, Magid DJ, McNamara RL, Parkosewich J, Loeb JM, Krumholz HM. Strategies for Reducing the Door-to-Balloon Time in Acute Myocardial Infarction. New England Journal Of Medicine 2006, 355: 2308-2320. PMID: 17101617, DOI: 10.1056/nejmsa063117.Peer-Reviewed Original ResearchConceptsST-segment elevationBalloon timeCatheterization laboratoryMyocardial infarctionFaster doorEmergency departmentPrimary percutaneous coronary interventionHospital strategiesIntracoronary balloon inflationPercutaneous coronary interventionAcute myocardial infarctionMinority of hospitalsEmergency medicine physiciansReperfusion treatmentCoronary interventionBalloon inflationMedicine physiciansMultivariate analysisHospitalInfarctionPatientsMedicaid ServicesSignificant reductionReal-time data feedbackData feedback