2020
Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features
Pathak R, Goldberg SB, Canavan M, Herrin J, Hoag JR, Salazar MC, Papageorge M, Ermer T, Boffa DJ. Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features. JAMA Oncology 2020, 6: 1741-1750. PMID: 32940636, PMCID: PMC7499246, DOI: 10.1001/jamaoncol.2020.4232.Peer-Reviewed Original ResearchConceptsNode-negative non-small cell lung cancerHigh-risk pathologic featuresNon-small cell lung cancerAdjuvant chemotherapyCell lung cancerPathologic featuresTumor sizeSurvival benefitCohort studyLung cancerNode-negative NSCLCEarly-stage non-small cell lung cancerCox proportional hazards regression modelHigh-risk clinicopathologic featuresProportional hazards regression modelsNational Cancer DatabaseRetrospective cohort studyTreatment-naive patientsAdjuvant chemotherapy useHigh-risk featuresAssociation of survivalHazards regression modelsImmortal time biasChemotherapy useEligible patients
2013
Use of New Treatment Modalities for Non-small Cell Lung Cancer Care in the Medicare Population
Vest MT, Herrin J, Soulos PR, Decker RH, Tanoue L, Michaud G, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Use of New Treatment Modalities for Non-small Cell Lung Cancer Care in the Medicare Population. CHEST Journal 2013, 143: 429-435. PMID: 23187634, PMCID: PMC3566996, DOI: 10.1378/chest.12-1149.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerStage I non-small cell lung cancerVideo-assisted thoracoscopic surgeryProportion of patientsOlder patientsCancer careNon-small cell lung cancer careEarly-stage non-small cell lung cancerStage non-small cell lung cancerEnd Results-Medicare databaseLung cancer careCell lung cancerCurative local therapyNew treatment modalitiesOverall useNew surgical techniqueType of treatmentNew radiation modalitiesRadiation therapy modalitiesSurgical resectionCurative therapyLocal therapyMore patientsThoracoscopic surgeryMean age