2024
Primary outcomes of the enhanced, EHR-facilitated cancer symptom control (E2C2) cluster-randomized, stepped wedge, pragmatic trial.
Cheville A, Pachman D, Kroenke K, Herrin J, Grzegorczyk V, Mitchell S, Griffin J, Ridgeway J, Austin J, Smith A, Chlan L, Tofthagen C, Ruddy K. Primary outcomes of the enhanced, EHR-facilitated cancer symptom control (E2C2) cluster-randomized, stepped wedge, pragmatic trial. Journal Of Clinical Oncology 2024, 42: lba12006-lba12006. DOI: 10.1200/jco.2024.42.17_suppl.lba12006.Peer-Reviewed Original ResearchElectronic patient-reported outcome measuresCollaborative care modelElectronic health recordsNumerical rating scaleCluster-randomizedPragmatic trialSymptom burdenAssociated with adverse health outcomesCCM-based interventionsPatient-reported outcome measuresHealth service outcomesSelf-management informationClinician decision supportPrimary outcomeCancer type or stageMulti-state health systemCancer symptom controlCluster randomized trialMedical oncology clinicAdverse health outcomesUsual careCare modelCare teamSymptom managementSymptom scores
2020
Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2)
Finney Rutten LJ, Ruddy KJ, Chlan LL, Griffin JM, Herrin J, Leppin AL, Pachman DR, Ridgeway JL, Rahman PA, Storlie CB, Wilson PM, Cheville AL. Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2). Trials 2020, 21: 480. PMID: 32503661, PMCID: PMC7275300, DOI: 10.1186/s13063-020-04335-w.Peer-Reviewed Original ResearchConceptsPragmatic clusterSymptom controlCancer patientsEvidence-based implementation strategiesModerate sleep disturbanceInadequate symptom controlSelf-management supportRural-dwelling patientsLevel of careTeam of cliniciansElectronic health recordsMixed-methods evaluationClinical outcomesCare guidelinesPhysical functionSleep disturbancesCollaborative careClinical trialsHybrid type 2Care modelFunctional limitationsPatientsEHR algorithmType 2Clinical staff
2017
Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer
Ruddy KJ, Van Houten HK, Sangaralingham LR, Freedman RA, Thompson CA, Hashmi SK, Jemal A, Haddad TC, Mougalian S, Herrin J, Gross C, Shah N. Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer. Breast Cancer Research And Treatment 2017, 164: 515-525. PMID: 28493045, DOI: 10.1007/s10549-017-4280-y.Peer-Reviewed Original ResearchConceptsAcute care useEarly-stage breast cancerCare useBreast cancerAdjuvant chemotherapyContemporary adjuvant chemotherapyAcute care needsCommercial insurance databaseEmergency department visitsED visit ratesRate of hospitalizationOncology Care ModelChemotherapy initiationChemotherapy regimenEligible patientsED visitsDepartment visitsTreatment regimenAcute careInsurance databaseAdministration periodAdjusted ratesCare modelCare needsVisit rates