A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation
Fretheim A, Zhang F, Ross-Degnan D, Oxman AD, Cheyne H, Foy R, Goodacre S, Herrin J, Kerse N, McKinlay RJ, Wright A, Soumerai SB. A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation. Journal Of Clinical Epidemiology 2014, 68: 324-333. PMID: 25499983, DOI: 10.1016/j.jclinepi.2014.10.003.Peer-Reviewed Original ResearchConceptsC-RCTsControl groupInterrupted time series studyConfidence intervalsConcurrent control groupHealth system interventionsHealth system evaluationControl arm dataInterrupted time series designIntervention armRandomized trialsControl group dataTrial dataTime-series studyTime series designHealth systemStudy designEffect estimatesTrialsInterventionSystem interventionsArm dataGroup dataRCTsGroup