2016
Mitochondrial Redox Signaling and Tumor Progression
Chen Y, Zhang H, Zhou HJ, Ji W, Min W. Mitochondrial Redox Signaling and Tumor Progression. Cancers 2016, 8: 40. PMID: 27023612, PMCID: PMC4846849, DOI: 10.3390/cancers8040040.Peer-Reviewed Original ResearchMitochondrial redox proteinsExcessive ROSRedox proteinsCancer cellsMitochondrial redox signalingMitochondrial oxidative phosphorylationCellular ROS levelsStress signalingRedox regulationROS functionTumor progressionRedox signalingMitochondrial roleApoptotic signalingCancer cell proliferationRedox-sensitive pathwaysTranscriptional factorsReactive oxygen species generationTumor suppressorOxidative phosphorylationDNA mutationsOxygen species generationCancer progressionBasal ROSCancer invasion
2010
Chapter 19 Thioredoxin and Redox Signaling in Vasculature—Studies Using Trx2 Endothelium-Specific Transgenic Mice
Min W, Xu L, Zhou H, Huang Q, Zhang H, He Y, Zhe X, Luo Y. Chapter 19 Thioredoxin and Redox Signaling in Vasculature—Studies Using Trx2 Endothelium-Specific Transgenic Mice. Methods In Enzymology 2010, 474: 315-324. PMID: 20609919, DOI: 10.1016/s0076-6879(10)74019-2.Peer-Reviewed Original ResearchConceptsReactive oxygen speciesCellular reactive oxygen speciesMitochondrial antioxidant systemVivo functional assaysTRX2 geneRedox signalingTransgenic miceRedox genesThioredoxin 2Functional analysisHuman diseasesFunctional assaysAntioxidant systemOxygen speciesGenesCritical roleEndothelial cell culturesCell culturesPrimary lineTrx2TransgenesisThioredoxinMitochondriaSignalingSpecies