A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma.
Totonchy MB, McNiff JM, Suozzi KC, Leffell DJ, Christensen SR. A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma. Dermatologic Surgery 2021, 47: 445-451. PMID: 33795563, DOI: 10.1097/dss.0000000000002923.Peer-Reviewed Original ResearchConceptsCutaneous squamous cell carcinomaPerineural invasionSquamous cell carcinomaAdverse outcomesNerve diameterHistopathologic featuresPNI scoreCell carcinomaExtratumoral perineural invasionRetrospective cohort studyCurrent staging systemHistopathologic scoring systemTumor-related deathNumber of nervesLogistic regression analysisMedian followNerve involvementCohort studyLocal recurrenceSurgical excisionStaging systemRisk factorsMedian numberHistopathologic slidesNerve structures